The objective of this study was to determine to relations between the depression level and the conflict resolution styles, marital adjustments of the depressed patients and to analyze the conflict resolution styles, marital adjustments of both the patients and their spouses as the possible predictors of depression levels. The research comprised 113 patients with major depression and their spouses. While there was a negative correlation between depression scores and positive and subordination conflict resolution styles subscales of the patients, there was a positive correlation between the depression scores and negative conflict resolution style subscale. Negative correlation was observed between the depression and marital adjustment scores of patients (p < 0.05). The conflict resolution styles and marital adjustment of depressed patients and their spouses are predictors of depression in patients.