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To review new advances in wound healing over the last decade relevant to facial plastic surgery, recent studies in wound healing and its clinical implications were evaluated. New biological and clinical products in wound healing have implications in facial plastic surgery. These products will alter the method with which we approach normal and poorly healing wounds. The US Food and Drug Administration approval of growth factor products signifies the beginning of a new age for actively promoting the healing of wounds for the surgeon. Some of these recent discoveries in wound healing relevant to the facial plastic surgeon are described.