SAT0766-HPR The factors affecting functional abilities in patients with juvenile idiopathic arthritis

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Abstract

Background

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in pediatric population and is characterized by a heterogeneous group of diseases that include chronic arthritis of unknown origin, which begins before 16 years of age (1). Patients with JIA commonly experience acute and chronic pain, decreased mobility, and joint stiffness leading to restrictions on functional ability and isolation from their peers (2).

Objectives

The aim of this study was to assess relationship between clinical features and functional ability and determine the factors affecting functional abilities in patients with JIA.

Methods

172 (aged 5–18 years) with JIA were included in this study. Socio-demographic data, clinical features (duration of disease, subtype of JIA, and number of involved joint) and functional ability were assessed with Childhood Health Assessment Questionnaire (CHAQ). Pain and overall well-being were measured using a Visual Analog Scale (VAS). Relations between the factors affecting functional abilities in JIA were assessed by multiple linear regression analysis

Results

The mean age was 10.71±3.47 and the mean disease duration was 5.41±3.53 years. Score of CHAQ was affected by number of involved joint (β=0.18, p<0.05), subtypes of JIA (β=- 2.75, p<0.01) and pain (β=0.15, p<0.05), but were not affected by age (β=-0.03, p>0.05), gender (β=-0.03, p>0.05) and disease duration (β=0.03, p>0.05). In addition to, significant difference was found between all CHAQ subscores (except of “walking”) of polyarticular and oligoarticular JIA (p<0.001). Functional abilities of patients with polyarticular JIA were lower than functional abilities of patients with oligoarticular JIA.

Conclusions

In the literature, it reported that functional activities were adversely affected in patients with JIA, when they compared with healthy subjects. In our study, we found that functional abilities were affected by subtypes of JIA, number of involved joint, and pain. But, these were not affected by age, gender, and disease duration in JIA. We suggest that subtypes of JIA, number of involved joint, and pain should be considered, when patients with JIA are directed to physical therapy program to encourage functional abilities.

Disclosure of Interest

None declared

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