The Good, the Bad, and the Ugly: Should We Completely Banish Human Albumin from Our Intensive Care Units?

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ImplicationsHuman albumin is still widely used in critically ill patients for volume replacement therapy or for correcting hypoproteinemia. Most meta-analyses on the value of albumin administration are over 15 yr old and raise more questions than they answer. With the help of a MEDLINE analysis, we examined more recent studies in humans using albumin. Most of these studies have recommended a very cautious use of albumin in critically ill patients.

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