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Until recently, anesthetists have focused on antibiotic administration and normothermia but have paid less attention to contamination in the anesthesia environment and its impact on surgical site infections. We implemented a simple intervention and tested its effect on anesthetic environment contamination between procedure start and finish. Of the baseline cases, 46% reached a critical predefined threshold of contamination compared with 12% of the intervention cases. A small behavioral change dramatically lowered contamination in the anesthesia environment.