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The purpose of this study was to describe the views of Luba-Kasai (a Congolese tribe) men on barriers inhibiting them from the prevention of mother-to-child transmission (PMTCT) of HIV and the resources they need to implement such prevention in Lusaka, Zambia. Twenty-one men were interviewed and the data were analyzed using qualitative content analysis. The barriers identified in the data were poverty, refugee status, absence of support arrangements, and the working culture in antenatal care, passivity, ignorance, marital disharmony, HIV-related stigma, and cultural characteristics, such as ways of being a man and religious beliefs. The resources were spiritual outlook on life, knowledge of HIV issues, support and availability of advanced health services, and satisfaction of basic needs. Improving male participation in PMTCT in this subpopulation presupposes cooperation between different sectors of society and inspiring trust in antenatal care.