Theranostic Treatment of Metastatic Bone Pain With 177Lu-DOTMP

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Radiochemical studies and biological evaluation in animal models have shown superior radiochemical properties and better clearance pattern for 177Lu-DOTMP compared with 177Lu-EDTMP, an agent recently proven to be efficacious and safe for metastatic bone pain palliation. This prompted us to initiate the clinical evaluation of 177Lu-DOTMP. The images represent the whole-body scans of a prostate cancer patient (man, 67 years) with skeletal metastases recorded after administering 3.7 GBq (100 mCi) of 177Lu-DOTMP.

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