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To report a novel intervention for the treatment of conjunctival lymphangiectasia—subconjunctival injection of bevacizumab.A 53-year-old white male presented with a 3-month history of right ocular discomfort and redness unresponsive to conventional topical treatment of lubricants and steroids. A clinical diagnosis of conjunctival lymphangiectasia was confirmed by biopsy. Bevacizumab (25 mg/mL) was injected subconjunctivally into the affected area.An improvement in the degree of conjunctival chemosis was evident at 5 days postinjection. At 1-month follow-up, symptoms had fully resolved. No recurrence had been observed at 3 years' follow-up.Subconjunctival bevacizumab injection may be an effective treatment for conjunctival lymphangiectasia.