1Stanford Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA.2Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA.3Sage Bionetworks, Seattle, WA.4Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University, Durham, NC.5Department of Electrical and Computer Engineering, Duke University, Durham, NC.6Bio Sepsis, Hospital Clínico Universitario de Valladolid/IECSCYL, Valladolid, Spain.7Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.8Department of Medicine, Cornell Medical Center, New York, NY.9Centre for Immunology and Allergy Research, Westmead Institute for Medical Research, Sydney, NSW, Australia.10Department of Intensive Care Medicine, Nepean Hospital, Sydney, Australia.11Nepean Genomic Research Group, Nepean Clinical School, University of Sydney, Sydney, NSW, Australia.12Marie Bashir Institute for Infectious Diseases and Biosecurity, Sydney, NSW, Australia.13Division of Infectious Diseases and International Health, Department of Medicine, Duke University, Durham, NC.14Durham Veteran’s Affairs Health Care System, Durham, NC.15Rady Children’s Institute for Genomic Medicine, San Diego, CA.16Division of Critical Care Medicine, Cincinnati Children’s Hospital Medical Center and Cincinnati Children’s Research Foundation, Cincinnati, OH.17Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH.18Department of Pharmacology, University of South Alabama, Mobile, AL.