1Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK2Clinical Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria3Neuroimmunology Program, Hospital Clinic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain4Zdravotni ustav se sidlem v Usti nad Labem, Centrum imunologie a mikrobiologie, Usti nad Labem, Czech Republic5Department of Neurology, Center of Clinical Neuroscience First Faculty of Medicine, General University Hospital and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic6Laboratory for CSF and Neuroimmunology, Topelex Ltd, Prague, Czech Republic7Department of Clinical Immunology, Odense University Hospital, Odense, Denmark8Institute of Clinical Research, University of Southern Denmark, Odense, Denmark9Department of Neurology, University of Pécs, Pécs, Hungary10Euroimmun AG, Lübeck, Germany11Klinikum rechts der Isar der TU München, Klinik für Neurologie, Munich, Germany12Department of Immunology and Biotechnology, University of Pécs, Pécs, Hungary13Clinical Neurobiology Unit, Neuroscience Institute Cavalieri Ottolenghi (NICO), University Hospital San Luigi Gonzaga, Regional Referring Multiple Sclerosis Centre, Orbassano, Italy14Department of Neurology, Azienda ULSS 9 Treviso, Treviso, Italy15Sanquin Diagnostic Services, Department of Immunopathology and Blood Coagulation, Amsterdam, The Netherlands16Department of Neurology, MS Centre ErasMS, Erasmus MC, Rotterdam, The Netherlands17Institute of Neurology, Medical University of Vienna, Vienna, Austria18Servei de Neurologia-Neuroimmunologia, Centre d'Esclerosi Múltiple de Catalunya (Cemcat), Vall d'Hebron Institut de Recerca, Hospital Universitari Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain19Neurology Department, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey20Department of Immunology, Istanbul University, Institute of Experimental Medicine, Istanbul, Turkey21NeuroCure Clinical Research Center (NCRC), Charité Universitätsmedizin Berlin, Berlin, Germany22Medical Faculty, Department of Neurology, Heinrich–Heine–University Düsseldorf, Düsseldorf, Germany23Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Germany24Department of Clinical Medicine, University of Bergen, Bergen, Norway25Department of Neurology, Haukeland University Hospital, Bergen, Norway26Faculty of Medecine RTH Laennec, Lyon Neurosciences Research Centre, Neuro–inflammation and Neuro–oncology Team, Lyon, France27Department of Neurology, University Hospital of Schleswig-Holstein, Campus Lübeck, Lübeck, Germany28Institute for Quality Assurance, Lübeck, Germany