Clinical Infectious Diseases. 38(6):910–912, MARCH 15TH, 2004

DOI: 10.1086/382075

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PMID: 14999639

Issn Print: 1058-4838

Publication Date: March 15th, 2004


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Successful Treatment of a Critically Ill Patient with Disseminated Coccidioidomycosis, Using Adjunctive Interferon-γ

Timothy Kuberski;Ronald Servi;Phillip Rubin;

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Abstract

Conventional antifungal therapy was not successful for a critically ill patient who had been hospitalized for 137 days in the intensive care unit with disseminated Coccidioides immitis infection and respiratory failure. The addition of interferon-γ to the therapeutic regimen resulted in improvement and discharge from the hospital. Adjunctive interferon-γ used in the successful treatment of severe coccidioidomycosis has not been reported previously.

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