Immune Reconstitution Inflammatory Syndrome Associated with Kaposi Sarcoma during Potent Antiretroviral Therapy

    loading  Checking for direct PDF access through Ovid


Rapidly progressive Kaposi sarcoma (KS) lesions with lymphadenopathy and tissue swelling occurred in a patient during antiretroviral treatment, despite an increased CD4+ lymphocyte count and decreased HIV-1 level and KS-associated herpesvirus replication, suggesting immune reconstitution inflammatory syndrome. Inflammation resolved coincident with decreases in the CD4+ lymphocyte count during paclitaxel treatment, whereas KS cleared only after prolonged antiretroviral therapy and chemotherapy.

    loading  Loading Related Articles