Effect of Compound LBK-149 on Antiarrhythmic Activity of Lidocaine in Rats with Arrhythmias and Disturbances in Lipid and Carbohydrate Metabolism

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Abstract

Antiarrhythmic activity of lidocaine during early occlusion and reperfusion arrhythmias decreased in rats with experimental disturbances in lipid and carbohydrate metabolism. The course of additional treatment with compound LBK-149 potentiated antiarrhythmic activity of lidocaine.

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