Comparative Efficiency of Intraperitoneal Interleukine-2 and Interferon-α in Rats with Experimental Endometriosis

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Abstract

Intraperitoneal injection of rat IFN-α and human IL-2 to rats with experimental endometriosis led to complete regression of endometrioid heterotopies in 50 and 60% cases, respectively. Retention of the endometrioid epithelium resulted in a significant reduction of proliferative activity of its cells, degree of vascularization, and number of macrophages in the leukocytic infiltration of endometrioid heterotopies.

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