Mechanisms of energy balance in obesity

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Maintains that the proper understanding of obesity requires a multifaceted approach and that behavioral considerations of eating and activity patterns do not account for the large between- and within-Ss variance associated with the energy-balance equation. Sources of adaptive and dispositional variance in metabolic rates are suggested to be a likely source of importance for the proper conceptualization and intervention of obesity. Five proposed mechanisms of metabolic variation are reviewed with consideration of the supporting evidence for each mechanism. The generalizability of some of the proposed mechanisms is considered to be limited because of the scope of past research. However, the roles of lipoprotein lipase in fat storage and brown adipose tissue in thermogenesis are possibilities for future research with humans. (103 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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