Transferrin-Binding Capacity by Rat Bone Marrow Populations Containing Different Proportions of Erythroid Cells

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Abstract

The transferrin-binding capacity of rat bone marrow cells and different erythroid-enriched populations from rat bone marrow has been studied and compared with that previously reported for pure reticulocyte populations. Two components with different transferrin-binding capacities were found. The one with higher affinity was present mainly in erythroid cells and showed an association constant similar to that observed in reticulocyte populations. The component with a lower transferrin affinity was observed mainly in bone marrow fractions containing low proportions of erythroid cells.

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