A Novel PCR-RFLP Assay for the Detection of the Single Nucleotide Polymorphism at Position +1440 in the Human CXCR2 gene

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We designed a novel PCR-RFLP assay to genotype for the CXCR2 +1440 (G/A) single nucleotide polymorphism, which provides a simple, low-cost, practical, and reproducible method. Allele frequencies in healthy Brazilian individuals were found to be 0.65% for allele A and 0.35% for allele G.

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