Prodrug research: futile or fertile?
Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs
Differences in binding properties of two proton pump inhibitors on the gastric H+,K+-ATPase in vivo
Stimulation of proliferation and migration of a colorectal cancer cell line by amidated and glycine-extended gastrin-releasing peptide via the same receptor
Peroxisome proliferator-activated receptor α regulates B lymphocyte development via an indirect pathway in mice
Kininogenase activity of Thalassophryne nattereri fish venom
Relation between the ability of some compounds to modulate the MRP1-mediated efflux of glutathione and to inhibit the MRPl-mediated efflux of daunorubicin
Catalase induces the expression of inducible nitric oxide synthase through activation of NF-κB and PI3K signaling pathway in Raw 264.7 cells
Differential modulation of PI3-kinase/Akt pathway during all- trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis
Effects of synthetic sphingosine-1-phosphate analogs on arachidonic acid metabolism and cell death
Ibuprofen-induced Walker 256 tumor cell death: cytochrome c release from functional mitochondria and enhancement by calcineurin inhibition
Effects of anandamide on the binding and signaling properties of M1 muscarinic acetylcholine receptors
Induction of Cdc25B expression by epidermal growth factor and transforming growth factor-α
Differential type 4 cAMP-specific phosphodiesterase (PDE4) expression and functional sensitivity to PDE4 inhibitors among rats, monkeys and humans
Kinetic analysis of interactions between human acetylcholinesterase, structurally different organophosphorus compounds and oximes
A gene expression signature for oxidant stress/reactive metabolites in rat liver
Influence of phenylalanine 120 on cytochrome P450 2D6 catalytic selectivity and regiospecificity: crucial role in 7-methoxy-4-(aminomethyl)-coumarin metabolism
A methylester of the glucuronide prodrug DOX-GA3 for improvement of tumor-selective chemotherapy
A novel therapy for acute hepatitis utilizing dehydroepiandrosterone in the murine model of hepatitis
Intrahepatic flow disturbance by clomipramine in the isolated perfused rat liver