Endoplasmic reticulum calcium release potentiates the ER stress and cell death caused by an oxidative stress in MCF-7 cells
Antitumor 1-nitroacridine derivative C-1748, induces apoptosis, necrosis or senescence in human colon carcinoma HCT8 and HT29 cells
Inhibition of the JAK-STAT3 pathway by andrographolide enhances chemosensitivity of cancer cells to doxorubicin
Induction of apoptosis by thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator UHRF1
Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells
Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action
The alkylating prodrug J1 can be activated by aminopeptidase N, leading to a possible target directed release of melphalan
Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death
Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling
Proton pump inhibitor Lansoprazole is a nuclear liver X receptor agonist
Activation of distinct P2Y receptor subtypes stimulates insulin secretion in MIN6 mouse pancreatic β cells
St. John's Wort reduces neuropathic pain through a hypericin-mediated inhibition of the protein kinase C γ and ε activity
GABAA receptor subtype selectivity underlying anxiolytic effect of 6-hydroxyflavone
Isoform distinct time-, dose-, and castration-dependent alterations in flavin-containing monooxygenase expression in mouse liver after 2,3,7,8-tetrachlorodibenzo- p -dioxin treatment
AMPK-mediated GSK3β inhibition by isoliquiritigenin contributes to protecting mitochondria against iron-catalyzed oxidative stress
Susceptibility to acetaminophen (APAP) toxicity unexpectedly is decreased during acute viral hepatitis in mice
Corrigendum to “Comparative pharmacology and computational modelling yield insights into allosteric modulation of human α7 nicotinic acetylcholine receptors” [Biochem. Pharmacol. 78 (2009) 836-843],