Organic cation transporter OCT/SLC22A and H+/organic cation antiporter MATE/SLC47A are key molecules for nephrotoxicity of platinum agents
Sirtuins and inflammation
Nephroblastoma overexpressed gene (NOV) enhances cell motility and COX-2 upregulation of human osteosarcoma involves αvβ5 integrin, ILK and AP-1-dependent pathways
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines
Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway
NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy
Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator
Inhibition of human leukocyte elastase, plasmin and matrix metalloproteinases by oleic acid and oleoyl-galardin derivative(s)
Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation
The N-terminal domain of human hemokinin-1 influences functional selectivity property for tachykinin receptor neurokinin-1
Evaluation of >in vitro PXR-based assays and >in silico modeling approaches for understanding the binding of a structurally diverse set of drugs to PXR
Modulation of Rad51, ERCC1, and thymidine phosphorylase by emodin result in synergistic cytotoxic effect in combination with capecitabine