BMP signaling in development and diseases : A pharmacological perspective
Toxico-pharmacological perspective of the Nrf2-Keap1 defense system against oxidative stress in kidney diseases
IκB kinase ε (IKKε) : A therapeutic target in inflammation and cancer
Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans
Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells
Morin inhibits STAT3 tyrosine 705 phosphorylation in tumor cells through activation of protein tyrosine phosphatase SHP1
Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress
ABT-737 resistance in B-cells isolated from chronic lymphocytic leukemia patients and leukemia cell lines is overcome by the pleiotropic kinase inhibitor quercetin through Mcl-1 down-regulation
L-Carnitine protects against arterial hypertension-related cardiac fibrosis through modulation of PPAR-γ expression
Anti-human VWF monoclonal antibody SZ-123 prevents arterial thrombus formation by inhibiting VWF–collagen and VWF–platelet interactions in Rhesus monkeys
ATP stimulates PGE2/cyclin D1-dependent VSMCs proliferation via STAT3 activation : Role of PKCs-dependent NADPH oxidase/ROS generation
Anti-obesity effects of 3-hydroxychromone derivative, a novel small-molecule inhibitor of glycogen synthase kinase-3
Thioredoxin-mimetic peptides (TXM) reverse auranofin induced apoptosis and restore insulin secretion in insulinoma cells
AMP-activated protein kinase as regulator of P2Y6 receptor-induced insulin secretion in mouse pancreatic β-cells
p63 involvement in poly(ADP-ribose) polymerase 1 signaling of topoisomerase I-dependent DNA damage in carcinoma cells
Transcriptome profiling and genome-wide DNA binding define the differential role of fenretinide and all-trans RA in regulating the death and survival of human hepatocellular carcinoma Huh7 cells
Osteoblasts survive the arsenic trioxide treatment by activation of ATM-mediated pathway