New paradigms in GPCR drug discovery
Role of sex steroids and their receptors in human preterm infants: Impacts on future treatment strategies for cerebral development
NOSH-aspirin (NBS-1120), a novel nitric oxide- and hydrogen sulfide-releasing hybrid has enhanced chemo-preventive properties compared to aspirin, is gastrointestinal safe with all the classic therapeutic indications
Autophagy exacerbates caspase-dependent apoptotic cell death after short times of starvation
Pharmacology of novel small-molecule tubulin inhibitors in glioblastoma cells with enhanced EGFR signalling
Combination therapy with bioengineered miR-34a prodrug and doxorubicin synergistically suppresses osteosarcoma growth
Inhibition of Kv channel expression by NSAIDs depolarizes membrane potential and inhibits cell migration by disrupting calpain signaling
OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion
Inhibition of epithelial growth factor receptor can play an important role in reducing cell growth and survival in adrenocortical tumors
Functional expression of the 11 human Organic Anion Transporting Polypeptides in insect cells reveals that sodium fluorescein is a general OATP substrate
A proposed mechanism for the adverse effects of acebutolol: CES2 and CYP2C19-mediated metabolism and antinuclear antibody production
Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells
Thermodynamics and kinetics of inhibitor binding to human equilibrative nucleoside transporter subtype-1
Use of physiologically based kinetic (PBK) modeling to study interindividual human variation and species differences in plasma concentrations of quercetin and its metabolites
Protein kinase C-dependent regulation of human hepatic drug transporter expression
In vitro and in vivo metabolism of N-adamantyl substituted urea-based soluble epoxide hydrolase inhibitors
Radiometric assay of ghrelin hydrolase activity and 3H-ghrelin distribution into mouse tissues
Glycosylation-dependent activation of epithelial sodium channel by solnatide