Steroid receptor coactivators present a unique opportunity for drug development in hormone-dependent cancers
Proprotein convertase inhibition: Paralyzing the cell's master switches
OP16, a novel ent-kaurene diterpenoid, potentiates the antitumor effect of rapamycin by inhibiting rapamycin-induced feedback activation of Akt signaling in esophageal squamous cell carcinoma
The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer
Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death
Cav1.2 channel current block by the PKA inhibitor H-89 in rat tail artery myocytes via a PKA-independent mechanism: Electrophysiological, functional, and molecular docking studies
Synthetic anti-endotoxin peptides inhibit cytoplasmic LPS-mediated responses
Testosterone regulates 3T3-L1 pre-adipocyte differentiation and epididymal fat accumulation in mice through modulating macrophage polarization
Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells
Rho kinase-dependent desensitization of GPR39; a unique mechanism of GPCR downregulation
Wnt/β-catenin signaling plays an essential role in α7 nicotinic receptor-mediated neuroprotection of dopaminergic neurons in a mouse Parkinson's disease model
Single nucleotide polymorphisms of ABCC2 modulate renal secretion of endogenous organic anions
MicroRNA hsa-miR-370-3p suppresses the expression and induction of CYP2D6 by facilitating mRNA degradation
Identification of enzymes responsible for nitrazepam metabolism and toxicity in human