Cake: a bioinformatics pipeline for the integrated analysis of somatic variants in cancer genomes

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Abstract

Summary:

We have developed Cake, a bioinformatics software pipeline that integrates four publicly available somatic variant-calling algorithms to identify single nucleotide variants with higher sensitivity and accuracy than any one algorithm alone. Cake can be run on a high-performance computer cluster or used as a stand-alone application.

Availabilty:

Cake is open-source and is available from http://cakesomatic.sourceforge.net/

Contact:

da1@sanger.ac.uk

Supplementary Information:

Supplementary data are available at Bioinformatics online.

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