LEAP: constructing gene co-expression networks for single-cell RNA-sequencing data using pseudotime ordering

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Abstract

Summary:

To construct gene co-expression networks based on single-cell RNA-Sequencing data, we present an algorithm called LEAP, which utilizes the estimated pseudotime of the cells to find gene co-expression that involves time delay.

Availability and Implementation:

R package LEAP available on CRAN

Contact:

jun.li@nd.edu

Supplementary information:

Supplementary data are available at Bioinformatics online.

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