The modeling language ML-Rules allows specifying and simulating complex systems biology models at multiple levels of organization. The development of such simulation models involves a wide variety of simulation experiments and the replicability of generated simulation results requires suitable means for documenting simulation experiments. Embedded domain-specific languages, such as SESSL, cater to both requirements. With SESSL, the user can integrate diverse simulation experimentation methods and third-party software components into an executable, readable simulation experiment specification. A newly developed SESSL binding for ML-Rules exploits these features of SESSL, opening up new possibilities for executing and documenting simulation experiments with ML-Rules models.Availability and implementation
ML-Rules is implemented in Java, SESSL and its bindings are implemented in Scala. The source code is available under open-source licenses:Availability and implementation
ML-Rules git.informatik.uni-rostock.de/mosi/mlrules2Availability and implementation
ML-Rules Quickstart (Graphical Editor) git.informatik.uni-rostock.de/mosi/mlrules2-quickstartAvailability and implementation
SESSL git.informatik.uni-rostock.de/mosi/sessl and sessl.orgAvailability and implementation
SESSL Quickstart (Experiment Template) git.informatik.uni-rostock.de/mosi/sessl-quickstartAvailability and implementation
Furthermore, Maven-compatible compiled packages of ML-Rules, SESSL, and the SESSL bindings are available from the Maven Central Repository at maven.org (org.sessl:* and org.jamesii: mlrules).Supplementary information
Supplementary data are available at Bioinformatics online.