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The cow milk angiogenin consumed by mice perorally penetrated from the gastrointestinal tract in the blood flow. In the experimental animals, the blood level of exogenous angiogenin first increased to reach a maximum, and then gradually decreased to zero. The dynamics of this process depends on the age of animals. The data obtained suggest that the cycle of perorally introduced cow milk angiogenin in blood is realized in the infantile-juvenile mice at a higher rate than in the adult-presenile mice.