Physiologically based pharmacokinetic (PBPK) modeling: It is here to stay!
PBPK as a tool in regulatory review
An industrial perspective on contemporary applications of PBPK models in drug discovery and development
Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs?
Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies
Utility of a physiologically–based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug–drug–disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice
From preclinical to human – prediction of oral absorption and drug–drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in an industrial setting: a workflow by using case example