Bipolar disorders
A new bipolar spectrum concept
Myo-inositol-1-phosphate (MIP) synthase
Bipolar disorders and suicidal behaviour
A double-blind, placebo-controlled trial of eicosapentanoic acid in rapid cycling bipolar disorder
Objectives
The volumetric findings in MRI brain study of bipolar twins and their healthy co-twins
Evaluation of parent-of-origin effect in bipolar affective disorder relating to susceptibility loci on chromosome 18
Comorbidity in the Dutch twin study on bipolar disorder
Are the structural brain deviations associated with bipolar disorder related to susceptibility genes?
Objectives
Prevalence of bipolar disorder
First episode bipolar disorder
Predictors of outcome in a representative population of bipolar disorder
Dimensions of psychopathology in bipolar disorder versus other affective and non-affective psychoses among an epidemiologically complete population
Relevance of the catatonic syndrome to the mixed manic episode
Objectives
Structural changes in bipolar disorder compared to schizophrenia
Cytoarchitectonic changes in bipolar disorder using stereology
The cytoarchitecture of the superior temporal gyrus in bipolar disorder using GLI-methodology
Abnormalities of prefrontal cortex SNARE complex proteins in bipolar disorder
Functional correlates of effect
Objectives
Does inositol signalling have a role in disease susceptibility and drug treatment of bipolar disorder?
Neuroplasticity and cellular resilience in bipolar disorder
Neurogenesis, neuroplasticity and severe affective disorder
Long-term synaptic plasticity in affective disorders
Objective
Do we need placebo control in maintenance studies in bipolar disorders?
Can we conduct some large simple trials in bipolar disorder?
Outcome measures in treatment trials in bipolar disorder
Limits of the applicability and generalizability of drug trials in mania
Objectives
Gene expression in bipolar disorder and schizophrenia
Immune activation, steroid resistancy and bipolar disorder
Expression of G-proteins and regulators of G-protein signalling in neutrophils of patients with bipolar disorder
Subtraction libraries for the molecular characterization of gene–environmental interactions in bipolar disorder
Infection, treatment and immune response in patients with bipolar disorder versus patients with major depression, schizophrenia or healthy controls
Objectives
A depression neurocircuit. Evidence from structural and functional studies
White matter lesions in bipolar disorder
Structural MRI and MRS abnormalities in bipolar disorder
Regional cerebral blood flow in bipolar disorder measured with PET
Behavioural insensitivity to sad facial expressions is associated with attenuated activation of amygdala and cingulate regions in patients with mania
Objectives
Response to ECT in major depression
Transcranial magnetic stimulation in patients with bipolar depression
Transcranial magnetic stimulation and neuroimaging
Transcranial direct current stimulation
TMS in depression. A treatment whose time has come?
Objectives
The mechanism of action of psychotherapy
Evidence for teaching bipolar disorder patients to identify early symptoms and obtain treatment
A randomized controlled study of cognitive therapy of relapse prevention for bipolar affective disorder
What is the role for psychotherapy in bipolar disorders?
Objectives
Life charts on a palmtop computer
Thyroid hormone augmentation with levothyroxine in bipolar depression
Interferon-alpha, cytokines and possible implications for mood disorders
Levetiracetam and ethosuximide in the treatment of acute mania in an open study with an on-off-on design
The switch – real threat or overestimated danger? Antidepressant-associated maniform states in acute treatment of patients with bipolar-I depression in the Munich study