The implications of a growing evidence base for drug use in elderly patients. Part 3. β-adrenoceptor blockers in heart failure and thrombolytics in acute myocardial infarction

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Abstract

β-adrenoceptor blockers and thrombolytic agents are of established value in the pharmacological management of heart failure and ST-elevation myocardial infarction, respectively. However, there is uncertainty as to whether these therapeutic strategies can be safely and effectively adopted in elderly patients with comorbidities, particularly in old-old individuals. This review focuses on these trials and the age-related efficacy and safety of these drugs.

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