Cryptococcal osteomyelitis of the spine

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We have treated seven patients with cryptococcal spondylitis.Five presented with a neurological deficit and one was HIV-positive. Amphotericin-B and 5-flucytosine were used in five patients and ketoconazole was given orally in the remaining two. Three patients made a complete neurological recovery. Since these lesions mimic spinal tuberculosis, which is commonly seen in our environment, we draw attention to the importance of obtaining a tissue diagnosis.

J Bone Joint Surg [Br] 1999;81-B:459-61.

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