Editorial
When all is lost…a severe myopathy with hypotonia from sodium channel mutations
Hypoxia, a turning point in migraine pathogenesis?
Inflammatory changes in very early Alzheimer’s disease
Targeting endoplasmic reticulum acetylation to restore proteostasis in Alzheimer’s disease
Immunosenescence of microglia and macrophages
Can physical exercise in old age improve memory and hippocampal function?
Loss-of-function mutations in SCN4A cause severe foetal hypokinesia or ‘classical’ congenital myopathy
Spinal cord injury-induced immune deficiency syndrome enhances infection susceptibility dependent on lesion level
Thalamic pain
Migraine induced by hypoxia
Non-invasive imaging of oxygen extraction fraction in adults with sickle cell anaemia
Normobaric hyperoxia markedly reduces brain damage and sensorimotor deficits following brief focal ischaemia
EPG5-related Vici syndrome
LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with distinct MRI appearance
Brain intra- and extracellular sodium concentration in multiple sclerosis
The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain
Longitudinal evidence for anterograde trans-synaptic degeneration after optic neuritis
Mapping neuroplastic potential in brain-damaged patients
Cerebellar atrophy in Parkinson’s disease and its implication for network connectivity
Brain propagation of transduced α-synuclein involves non-fibrillar protein species and is enhanced in α-synuclein null mice
GABA transmission via ATP-dependent K+ channels regulates α-synuclein secretion in mouse striatum
Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
MicroRNA-132 and early growth response-1 in nucleus basalis of Meynert during the course of Alzheimer’s disease
Diverging longitudinal changes in astrocytosis and amyloid PET in autosomal dominant Alzheimer’s disease
Improved proteostasis in the secretory pathway rescues Alzheimer’s disease in the mouse
CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease
Mentalizing the body
On the right side? A longitudinal study of left- versus right-lateralized semantic dementia
Autism
Essential tremor in ‘The tremulous hand of Worcester’
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Parsing the differences in affected with LHON
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Autosomal recessive cerebellar ataxia caused by a homozygous mutation in PMPCA
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