Comparison of two Bayesian approaches to dose-individualization for once-daily aminoglycoside regimens
Cytochromes P450 mediating the N-demethylation of amitriptyline
Disposition and effects of flurbiprofen enantiomers in human serum and blister fluid
Pharmacokinetics and systemic effects of inhaled fluticasone propionate in healthy subjects
Evidence for both in vivo and in vitro interaction between vigabatrin and alanine transaminase
Picumeterol: dissociation of improvement in lung function and reduction of airways hyperresponsiveness in asthmatics
Under-reporting of adverse drug reactions in general practice
The risk of acute liver injury associated with cimetidine and other acid-suppressing anti-ulcer drugs
Tamoxifen metabolic patterns within a glioma patient population treated with high-dose tamoxifen
The mechanism of cyclosporine toxicity induced by clarithromycin
I-Methylxanthine derived from caffeine as a pharmacodynamic probe of oxypurinol effect
A pharmacokinetic and pharmacodynamic interaction study between nebivolol and the H2-receptor antagonists cimetidine and ranitidine
Evaluation of corticotropin releasing factor stimulation and basal markers of HPA-axis suppression in asthmatic patients
Lipid-lowering drugs: are we treating the appropriate population?
A new in vitro method for measuring protein binding of drugs
An immunoprecipitation technique for detection of antibodies to novel drug-induced hepatic antigens
Immunochemical identification of modified hepatic protein adducts which could be involved in the hepatotoxicity of diclofenac
Formation of the CE3CO-protein antigens implicated in the pathogenesis of halothane hepatitis is catalyzed in human liver microsomes in vitro by CYP 2E1
The metabolism of MPTP by CYP2D6 and the demonstration of CYP2D6 mRNA in human brain by in situ hybridisation
Generation of a functional human monooxygenase system in Escherichia coli
Comparative bone metabolism effects of inhaled budesonide and fluticasone propionate in asthmatic patients
Regional deposition in the human airways of inhaled [11C]-nicotine vapour and cigarette smoke and body distribution of [11C]-nicotine visualized by positron emission tomography (PET)
Acute dosing with female sex hormones does not alter vascular angiotensin converting enzyme activity or fasted lipids in male volunteers
Regional distribution of glutathione transferase π immunoreactivity in human coronary arteries
The human D2 dopamine receptor: relationship between exonic gene variants and receptor binding characteristics in vivo
Peculiarities in the digit symbol substitution tests
The metabolism of losartan to the active metabolite E-3174 in subjects who are extensive and poor metabolizers of debrisoquine (CYP2D6) or mephenytoin (CYP2C19)
Uptake and metabolism of ethidium bromide by rat hepatocytes
Effect of drug treatment on hepatic cytochrome P450 and b5 levels in Leishmania donovani infected mice
Quantitative assessment of cytochrome P450 mRNAs in liver needle biopsies
Cytochrome P450 in fetal tissues, as assessed by mRNA quantitation and protein expression
Gene expression of target enzyme for intervention therapy in prostatic disease