Pharmacoeconomics: evaluating the evaluators
Population pharmacokinetics of lamotrigine monotherapy in patients with epilepsy: retrospective analysis of routine monitoring data
Lack of inhibitory effect of cimetidine on caffeine metabolism in children using the caffeine breath test
Concentrations and effects of zopiclone are greatly reduced by rifampicin
Pharmacokinetic and pharmacodynamic interaction trial after repeated oral doses of imidapril and digoxin in healthy volunteers
Natriuretic efficiency of frusemide as a consequence of drug input rate
Intra-arterial substance P mediated vasodilatation in the human forearm: pharmacology, reproducibility and tolerability
Characterization of angiotensin-II effects on cerebral and ocular circulation by noninvasive methods
Dopamine natriuresis in salt-repleted, water-loaded humans: a dose-response study
Genetics and the therapy of cardiovascular disease
Genetic basis for ethnic variation in the nature of hypertension
Techniques for the analysis of candidate genes for ischaemic heart disease
Renin-angiotensin system genes and cardiovascular disease
Influence of mutations of nitric oxide synthase and GSα on the incidence and treatment of ischaemic heart disease and hypertension
Oestrogen and cardiovascular disease
What does the pharmaceutical industry expect from genetic analysis in cardiovascular disease?
Venous constrictor responses to angiotensin II in the human forearm vascular bed
Adrenomedullin produces dilatation in human dorsal hand veins
Appropriateness of use of gastric decontamination procedures in poisoned patients
The influence of gender on the rate of volume increase of platelets exposed to weak acid from patients with essential hypertension
Effects of nitric oxide synthase inhibition and l-arginine on exercise haemodynamics
The M1-cholinoreceptor antagonist pirenzepine causes, in low doses, negative chronotropic effects in healthy volunteers
Extrapulmonary β2-adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers
Lung absorption of salbutamol given by dry powder inhaler and small volume antistatic metal spacer
The effects of topical doxepin cream and oral terfenadine on the cutaneous responses to histamine and substance P in human skin
Saquinavir pharmacokinetics alone and in combination with ritonavir
The effect of acute melatonin administration on the oxytocin response to increased plasma osmolality in man
Initial monoamine oxidase-A inhibition by moclobemide does not predict the therapeutic response in patients with major depression [1],
Abnormal saccadic distractibility and effects on antisaccade task subcomponents in human subjects in response to single doses of chlorpromazine and lorazepam
Protocol evaluation
Reproducibility of elbow width measurement used in the assessment of body frame size in metropolitan life tables
Plasma antioxidant status
24 h blood pressure monitoring and steady-state pharmacokinetics of felodipine metoprolol extended release tablet
A study of the effects of MK-462 (rizatriptan), clonidine and sumatriptan on autonomic function
Oestrogen-containing hormone replacement therapy in postmenopausal women: anti-rather than pro-oxidant
Effect of vitamin E supplementation in hyperlipidaemic patients
Contractile function is reduced in surgically-prepared human saphenous vein
The role of the potassium-ATP channel in forearm endothelial-dependent vascular responses
The role of nitric oxide in reactive hyperaemia in the human forearm
Impaired endothelial dependent responses, without impaired basal or stimulated nitric oxide production, in the forearm vasculature of non-insulin dependent diabetics
The effect of cyclooxygenase inhibition on forearm vascular responses to endothelin-1 in patients with NIDDM
The effect of cyclooxygenase inhibition on forearm vascular responses to endothelin-1 in healthy volunteers
Pharmacokinetics of fluticasone propionate inhaled from the Diskhaler® and the Diskus® powder devices in healthy subjects
Pharmacokinetics of fluticasone propionate inhaled from the Diskhaler® and the Diskus® powder devices in asthmatic patients
Lung bioavailability of salbutamol given by breath-activated pressurised aerosol and dry powder inhaler devices
Aerosols of bradykinin do not cause retrosternal chest discomfort and rarely evoke cough in mild asthmatics
The effect of exogenous melatonin on cortisol, prolactin and growth hormone secretion in man
Pharmacokinetics of mercaptopurine: plasma drug and red cell metabolite concentrations after an oral dose
Kinetic analysis of in vitro drug metabolism data: a literature survey
The bioavailability of stored epoetin beta in volunteer dialysis patients
Is there a pharmacodynamic interaction between ciprofloxacin and fenbufen?
Paracetamol poisoning in the north east of England
Development of a radioreceptor assay for human α-adrenoceptor subtypes: application to tamsulosin and terazosin pharmacokinetics
CYP2E1
Disposition and toxicity of antimalarial agents in human neutrophils: implications for drug safety
Dexamethasone metabolism by human liver and kidney in vitro and use of putative molecular models of CYP17 and CYP3A4
Kinetic analysis of heterologously expressed CYP2D6 and comparison with the human liver microsomal enzyme
Demonstration of the cytotoxicity of the chemically reactive metabolite of clozapine using a novel in vitro assay
An assessment of the time to onset of anti-emetic activity from the ondansetron suppository in the ipecacuanha model of emesis
Comparison of the effects of moclobemide and selegiline on tyramine-evoked mydriasis in man
Effects of befloxatone on EEG and cognitive functions in elderly subjects
Effect of age and facets of idiopathic parkinsonism on serum concentrations of tumour necrosis factor-α
Effects of antipsychotic medication of visual function in schizophrenic patients
Serum concentrations of interleukin-6 in sufferers from idiopathic parkinsonism and controls
Lack of a pharmacokinetic interaction between ropinirole and theophylline in parkinsonian patients
Audit of hospital prescribing
The oral bioavailability of pentosan polysulphate sodium (PPS) in healthy volunteers
Population pharmacokinetics of ropinirole in patients with Parkinson's disease