Pharmacovigilance: towards the next millennium
Use of the UK General Practice Research Database for pharmacoepidemiology
Pharmacovigilance in the pharmaceutical industry
Nitric oxide in the human cardiovascular system-SKB lecture 1997
Endothelin-1 induces vasodilation in human skin by nociceptor fibres and release of nitric oxide
The influence of nifedipine and captopril on liver blood flow in healthy subjects
Distribution and excretion of sertraline and N-desmethylsertraline in human milk
Distribution and excretion of venlafaxine and O-desmethylvenlafaxine in human milk
Assessment of hepatic blood flow using continuous infusion of high clearance drugs
Pharmacokinetics of bambuterol in healthy subjects
Pharmacokinetics of bambuterol in subjects homozygous for the atypical gene for plasma cholinesterase
Absorption kinetics of oral sotalol combined with cisapride and sublingual sotalol in healthy subjects
Verapamil SR and trandolapril combination therapy in hypertension-a clinical trial of factorial design
Different standards for reporting ADRs to herbal remedies and conventional OTC medicines: face-to-face interviews with 515 users of herbal remedies
Variability in trough plasma saquinavir concentrations in HIV patients-a case for therapeutic drug monitoring
Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease
Effect of the CYP2C9*2 genetic polymorphism on the bioactivation of sulphamethoxazole
Drug metabolism, acetylation, structure
Sulindac-associated injury: an animal model
In vivo metabolism of eugenol and isoeugenol following topical application in male F344 rats
Influence of genetic polymorphism on the pharmacokinetics of amitriptyline and nortriptyline: a NONMEM analysis
Dinitrochlorobenzene-mediated glutathione depletion in cultured human keratinocytes
Can human cardiac β2-adrenoceptors undergo agonist-induced desensitisation? An in vivo study in healthy volunteers
Association of β2-adrenoceptor polymorphism with vascular reactivity in humans
Direct vascular effects of acetazolamide in humans
The role of adenosine in the vasodilator response to insulin in humans
Investigation of substrate structure activity relationships (SSAR) for cytochrome P450 2C19
Prediction of intrinsic clearance of CYP2C9 substrates in man using hepatic microsomes : importance of K m
Halofantrine and chloroquine inhibit CYP2D6 activity in healthy Zambians
The interaction of terfenadine with CYP2D6: an in vitro and molecular modelling study
Population pharmacokinetics of methadone in opiate users: adaptive changes in kinetics from single dose to steady state
Role of CYP2C in the bioactivation of the oral contraceptive steroid desogestrel in vitro
Cytochrome P4503A4 is responsible for the metabolism of 3-ketodesogestrel in vitro
The effect of chronic HIV infection on the cytotoxicity of antiretroviral agents in vitro
CYP3A4-mediated metabolism of the HIV protease inhibitor saquinavir
The effect of chronic HIV infection on the intracellular activation of nucleoside analogues in vitro
The intracellular activation of ddI (didanosine) in combination with other nucleoside analogues in vitro
The in vitro metabolism of 6-mercaptopurine by human liver cytosol
Product inhibition of phenytoin and diazepam metabolism in vitro and its significance in predicting intrinsic clearance in vitro
Sigmoidal kinetics of CYP3A substrates: an approach for scaling dextromethorphan metabolism in rat microsomes and isolated hepatocytes to predict in vivo clearance
Sigmoidal kinetics of CYP3A4: the simultaneous metabolism and binding of testosterone and diazepam
Inhibition of rat cytochrome P450-dependent metabolism by ketoconazole and fluconazole in vitro
The cytokine response to perioperative leucodepletion during limb salvage surgery
The hidden hazards of blood transfusion during abdominal aortic aneurysm (AAA) repair
Cytokine assay kits in clinical trials: a comparative study