Effect of severe renal impairment on the pharmacokinetics of azimilide following single dose oral administration
Pharmacokinetics and safety of JTE-522, a novel selective cyclooxygenase-2 inhibitor, in healthy male volunteers
Development and validation of limited sampling strategies for prediction of the systemic exposure to the novel anticancer agent E7070 (N-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide)
Pharmacodynamic effects and pharmacokinetics of a new HMG-CoA reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers
Pharmacokinetic and pharmacodynamic profile following oral administration of the phosphodiesterase (PDE)4 inhibitor V11294A in healthy volunteers
Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet®) with concomitant administration of ketoconazole in healthy subjects
In vitro–in vivo correlations for drugs eliminated by glucuronidation
The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women
Genetic polymorphisms in human CYP2A6 gene causing impaired nicotine metabolism
Validation of a new fluorogenic real-time PCR assay for detection of CYP2C9 allelic variants and CYP2C9 allelic distribution in a German population
A clinical audit of the prescribing of celecoxib and rofecoxib in Australian rural general practice
Drug reimbursement
Spatial distribution of 8-methoxypsoralen penetration into human skin after systemic or topical administration
Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2
Effect of plastic spacer handling on salbutamol lung deposition in asthmatic children
Prevalence of factitious hypoglycaemia associated with sulphonylurea drugs in France in the year 2000
Penetration of fosfomycin into the parenchyma of human brain
Does age increase the risk of adverse drug reactions?
The effect of CYP2C19 polymorphism on the pharmacokinetics and acid-inhibitory effects of oral lansoprazole and omeprazole
The International Quality of Life Study of patients with angina pectoris on nitrate therapy
Randomized phase I and pharmacological study of weekly or 2-weekly gemcitabine and cisplatin in advanced non-small cell lung cancer
Pharmacokinetics of vancomycin in (pre)term neonates and influence of covariates
Biomarkers for the effects of benzodiazepines in healthy volunteers
Interventions to obtain an early switch from intravenous to oral antibiotic therapy in a Dutch teaching hospital
Motilin kinetics and effects on proximal stomach in patients with functional dyspepsia (FD) and healthy volunteers
A recirculatory model for tissue plasminogen activator with saturable endothelial binding
Adherence to and dosing of statins differs according to apolipoprotein E-genotypes
Patterns of lipid lowering drug use after the withdrawal of cerivastatin
Nasal drug delivery to the cerebrospinal fluid
REM sleep reduction as a biomarker for the effects of antidepressants in healthy volunteers
Bosentan, a dual endothelin receptor antagonist, activates the pregnane X nuclear receptor
Dipyridamole increases interstitial adenosine during intermittent isometric exercise but does not augment the pressor reflex