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Rational prescribing, appropriate prescribing
Optimization of drug prescribing
Metabolic inertia in contracting skeletal muscle
Oral contraception does not alter single dose saquinavir pharmacokinetics in women
Population pharmacokinetics of piperaquine in adults and children with uncomplicated falciparum or vivax malaria
Concentration-time profile for perhexiline and hydroxyperhexiline in patients at steady state
Pharmacokinetic evaluation of a new oral sustained release dosage form of tramadol
The effect of rosuvastatin on oestrogen & progestin pharmacokinetics in healthy women taking an oral contraceptive
CYP2D6 and CYP3A4 involvement in the primary oxidative metabolism of hydrocodone by human liver microsomes
Factors affecting variability in distribution of tacrolimus in liver transplant recipients
Impact of a short postgraduate course in rational pharmacotherapy for general practitioners
Trends in accessibility to medicines for children in New Zealand
The effect of hypertension and hypercholesterolemia screening with subsequent intervention letter on the use of blood pressure and lipid lowering drugs
Have COX-2 inhibitors influenced the co-prescription of anti-ulcer drugs with NSAIDs?
Influence of mild liver impairment on the pharmacokinetics of tezosentan, a drug excreted unchanged into bile
Tizanidine is mainly metabolized by cytochrome P450 1A2 in vitro
Experimental Therapeutics
Improving the quality of antibiotic treatment in a Dutch hospital
Population pharmacokinetics of nelfinavir in hiv-1-infected children
Bayesian pharmacokinetically guided dosing of paclitaxel in patients with non-small cell lung cancer
Cardioversion of atrial fibrillation with a loading dose of flecainide tablets or an oral solution of a mixture of flecainide and cisapride
Patient, doctor, and organisational factors affecting hypertension management in patients with type 2 diabetes
Determination of alcohol infusion rate by clamping of breath alcohol concentration - a comparison with modelled infusion regimens based on individual pharmacokinetics
Teaching resource centre (TRC)
Trends in antihypertensive drug prescribing in dutch general practice from 1996 to 2000
Tacrolimus, but not cyclosporine, dose requirement is correlated with CYP3A5*3 and CYP3A4*1B genotype
A Phase I, randomized, open-label, parallel-cohort, dose-finding study of elacridar (GF 120918) in combination with 2.0 mg oral topotecan in cancer patients
Oral bioavailability of docetaxel in combination with OC 144-093 (ONT-093)
The effectiveness of HMG-COA reductase inhibitors is affected by ACE insertion deletion polymorphism
Determinants of persistence with statin use in daily medical practice
Nasal drug delivery to the cerebrospinal fluid
When are antimicrobial treatment guidelines not followed?
Academic fluoroquinolone prescribing, resistance and impact of guidelines
Reliability of reported ingestion in paracetamol overdose
Amoxicillin pharmacokinetics in (pre)term neonates
Prevalence and determinants of undertreatment of hypertension in the Netherlands
Thiazide diuretics and the risk of hip fracture
Electro-encephalographic surrogate measures fail to describe the pharmacodynamic interaction between ketamine and propofol
Bioavailability of ibuprofen from hot-melt extruded mini-matrices
Human adenosine kinetics measured by microdialysis
Correlation between riluzole clearance and CYP1A2 activity in patients with amyotrophic lateral sclerosis
Calcitonin gene-related peptide-induced vasodilation in the human forearm
The risk of overanticoagulation in patients with cytochrome P450 CYP2C9*2 or CYP2C9*3 alleles on acenocoumarol or phenprocoumon
Determinants of elevations of lithium serum levels into the toxic range