Physiologically based pharmacokinetic modelling
Physiologically based pharmacokinetic modelling of the three-step metabolism of pyrimidine using 13C-uracil as an in vivo probe
Semi-mechanistic pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of artemisinin
Assessment of different methods of inhalation from salbutamol metered dose inhalers by urinary drug excretion and methacholine challenge
Vasodilator effects of the endothelin ETA receptor selective antagonist BMS-193884 in healthy men
Polymorphisms in genes encoding acetylsalicylic acid metabolizing enzymes are unrelated to upper gastrointestinal health in cardiovascular patients on acetylsalicylic acid
Gender specific association of CYP2C9*3 with hyperlipidaemia in Chinese
Sulphation of o-desmethylnaproxen and related compounds by human cytosolic sulfotransferases
Dramatic change in prescribing of hormone replacement therapy in the Netherlands after publication of the Million Women Study
Usage of paracetamol-containing combination analgesics remains high in primary care
Obstacles and solutions for spontaneous reporting of adverse drug reactions in the hospital
Effects of grapefruit juice on the pharmacokinetics of acebutolol
Nasal septal perforation enlargement related to topical ocular steroids
Interstitial pneumonitis during lamotrigine therapy
Ocular side-effects of tolterodine and oxybutynin, a single-blind prospective randomized trial
Ocular side-effects of tolterodine and oxybutynin, a single-blind prospective randomized trial
Relationship between serotonergic antidepressants and worsening of symptoms of Parkinson's disease
MDR-1 and CYP 3A gene polymorphisms and 12H AUC pharmacokinetics of Tacrolimus
A reanalysis of two studies that reported contrasting results on the association between statin use and risk of fracture in the same data source
Measured mycophenolic acid concentrations after administration of mycophenolate sodium (Myfortic®) are higher with EMIT compared to HPLC
Effects of utilization of computer based teaching (CBT) programs on test performance
Changes in medication in relation to epilepsy-related hospitalization
Patient counselling by community pharmacists at discharge from hospital
Lack of analgesic effect form topical morphine in painful arterial leg ulcers
Classification and occurrence of clinically significant drug-interactions with 5-fluorouracil/leucovorin in patients with colorectal cancer
Determinants of the elimination of methotrexate and 7-hydroxy-methotrexate following high-dose infusional methotrexate
The beta-blocker nebivolol and exercise-capacity in patients with mild hypertension
Valproic acid-induced metabolic encephalopathy, a life threatening complication a case report and pathofysiological mechanisms
Potassium channel blockade restores the attenuated noradrenaline sensitivity in human endotoxemia
Effects of a contraceptive vaginal ring delivering nestorone® and ethinyl estradiol, and a combined oral contraceptive containing levonorgestrel, on markers of arterial disease
Multiple-dose tolerability, safety, pharmacokinetics, and pharmacodynamics of the urotensin-II receptor antagonist palosuran in healthy human subjects
Prescribing for heart failure in Europe
Effect of age on P-glycoprotein blood brain barrier transport function studied with [11C](R)-verapamil and PET
Characteristics and predicting factors of adherence in patients with rheumatoid arthritis
Anti-Inflammatory effects of rosiglitazone in type 2 diabetes mellitus patients
Cyclosporine interacts with mycophenolate mofetil by inhibiting the multidrug resistance-associated protein 2
The influence of ethnicity on anti-hypertensive drug effects (a Dutch study with 3 ethnic groups)
Duration of response on tamoxifen in advanced breast cancer depends on CYP2C19 genotype
Imipramine dose requirement in depressed patients is predicted by CYP2D6 functional gene dosage
Elucidating the mechanism of lithium acquired nephrogenic diabetes insipidus in patients under chronic lithium treatment
Reviewers for 2005