TP receptor antagonists (TXRAs): expensive irrelevance or wonder drugs strangled at birth?
Denosumab
Interpreting population pharmacokinetic-pharmacodynamic analyses – a clinical viewpoint
Understanding the time course of pharmacological effect: a PKPD approach
Current progress in pharmacogenetics
Slow-release oral morphine for opioid maintenance treatment: a systematic review
Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis
A new topical formulation enhances relative diclofenac bioavailability in healthy male subjects
A pharmacokinetic and safety study of single dose intravenous combretastatin A4 phosphate in Chinese patients with refractory solid tumours
Temporal linear mode complexity as a surrogate measure of the effect of remifentanil on the central nervous system in healthy volunteers
Pharmacokinetic–pharmacodynamic relationships of central nervous system effects of scopolamine in healthy subjects
Modelling of pain intensity and informative dropout in a dental pain model after naproxcinod, naproxen and placebo administration
Central nervous system effects of the interaction between risperidone (single dose) and the 5-HT6 antagonist SB742457 (repeated doses) in healthy men
Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors
Prospective analysis of the impact of VEGF-A gene polymorphisms on the pharmacodynamics of bevacizumab-based therapy in metastatic breast cancer patients
Evolution of paediatric off-label use after new significant medicines become available for adults: a study on triptans in Finnish children 1994–2007
All-cause mortality of elderly Australian veterans using COX-2 selective or non-selective NSAIDs: a longitudinal study
Effects of safety warnings on prescription rates of cough and cold medicines in children below 2 years of age
Naloxone decreases the inhibitory effect of alprazolam on the release of adrenocorticotropin/cortisol induced by physical exercise in man
Lopinavir/ritonavir population pharmacokinetics in neonates and infants
Effect of lamotrigine on the PR interval in healthy subjects
Lamotrigine does not prolong QTc in a thorough QT/QTc study in healthy subjects, Dixon et al . 2008; request for publication of PR interval data
Safety of ibuprofen vs . paracetamol
Reply to letter by Peterson & Naunton [safety of ibuprofen vs . paracetamol],
Generic substitution: a need for clarification
Generic substitution: authors' response
New Drugs and Targets for Asthma and Chronic Obstructive Pulmonary Disease (CDPD)
mTOR Pathway and mTOR Inhibitors in Cancer Therapy
Assessment of dietary salt intake among patients with resistant hypertension
A novel method for analyzing Doppler blood velocity waveforms may reveal early microvascular disease. Studies of the retrobulbar circulation in type 1 diabetes and grade 1 hypertension
Amiloride has a more favourable effect on glucose tolerance than hydrochlorothiazide in the treatment of essential hypertension - Results of a double-blind, placebo controlled, randomized crossover study
Differential effects of vasodilators on human forearm muscular conduit arteries and resistance vessels
Improvement of endothelial function by tetrahydrobiopterin (BH4) supplementation does not alter aortic stiffness in patients with rheumatoid arthritis
Aspirin has little additional ex vivo anti-platelet effects in healthy volunteers receiving prasugrel
A pilot survey to assess the effectiveness of the electronic discharge letter to communicate medication changes to primary care following patient discharge from an acute medical unit
Impact of the anticholinergic risk score (ARS) on functional status and adverse outcomes in older hospitalized patients
Non-steroidal anti-inflammatory drugs and stroke risk: a systematic review and meta-analysis of the observational literature
Cyclophilin A is a damage associated molecular pattern that mediates paracetamol-induced liver injury
A study to determine the effect of oral N-acetyl-Lcysteine on platelet-leucocyte interaction in patients with type-2 diabetes
Modelling COPD exacerbations: Inhaled LPS challenge in smokers
Effect of a single dose of oral metformin on sodium absorption and chloride secretion across human airway epithelium
Fibronectin is regulated during microbial lung injury and mediates chronic inflammation
Prescribing in the elderly audit at Blackpool Victoria Hospital
Drug history and allergy status - Who Is best at obtaining this in acute medical admissions?
A survey to determine the patients' views on generic substitution
Improving oxygen prescribing and administration: an audit cycle and survey
Survey of ICD-10 coding of hospital admissions due to recreational drug toxicity
Impact of the drug burden index (DBI) on functional status and adverse outcomes in older hospitalized patients
Topical metformin inhibits chloride secretion but not sodium absorption across human nasal epithelium
Effects of n-3 highly unsaturated fatty acids on human platelet mitochondria
Publication bias: extent of unreported outcomes in conference abstracts and journal articles when compared with the full report in the GSK trials register
Azathioprine metabolism in autoimmune hepatitis
Comparison of six commonly used QT correction formulae and three parameter estimation methods
National pharmacovigilance websites: clarity and communication
Review of the pharmacokinetic profile of novel fentanyl transmucosal formulations
Cannabinoid induced vasorelaxation of human mesenteric arteries
Thiopurine methyltransferase activity in the clinical management of childhood acute lymphoblastic leukaemia
Anti-inflammatory activity through Fpr2 in a mouse model of global cerebral ischaemia/reperfusion
Improving the recording and assessment of breakthrough analgesia in a hospice setting
Computer molecular modelling of the p22phox protein structural changes linked to C242T polymorphism
Positron emission tomography of atherosclerosis
The role of an N-terminal aspartic acid residue (D67), highly conserved in Family B GPCRs, in the synthesis and traffi cking of the GLP-1 receptor
Quantification of the benefits of Pabrinex® in alcohol dependent patients using a brief Nutritional Deficiency Assessment
Efficacy and safety of analgesia in primary health care elderly patients with low back pain
An audit of prescribing errors and a report of junior doctors' awareness and perceptions after feedback Intervention by a pharmacist in a UK hospital
Model-based selection of paediatric dosing regimes: the antimalarial combination atovaquone-proguanil
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