Pharmacometrics: so much mathematics and why planes achieve their destinations with almost perfect results …
Editors' report for 2014, November 2014
Methods and software tools for design evaluation in population pharmacokinetics–pharmacodynamics studies
Clinical pharmacology = disease progression + drug action
A genetic algorithm based global search strategy for population pharmacokinetic/pharmacodynamic model selection
What do we learn from repeated population analyses?
Combining the ‘bottom up’ and ‘top down’ approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data
Population pharmacokinetic–pharmacodynamic modelling in oncology: a tool for predicting clinical response
Pharmacokinetic–pharmacodynamic modelling in anaesthesia
Paediatric models in motion: requirements for model-based decision support at the bedside
Modelling the time course of antimalarial parasite killing: a tour of animal and human models, translation and challenges
Model-based clinical drug development in the past, present and future: a commentary
The role of concentration−effect relationships in the assessment of QTc interval prolongation
Covariate selection in pharmacometric analyses: a review of methods
Model-based evaluation of drug-induced QTc prolongation for compounds in early development
Reviewers for 2014