Issue Highlights
Drug-induced Raynaud's phenomenon: beyond β-adrenoceptor blockers
Adverse drug event reporting systems: a systematic review
Japanese regulation of biosimilar products: past experience and current challenges
Pharmacokinetics, pharmacodynamics, short term efficacy and safety of RCT-18, a novel BLyS/APRIL fusion protein, in patients with rheumatoid arthritis
E-learning in order to improve drug prescription for hospitalized older patients: a cluster-randomized controlled study
A randomized phase l pharmacokinetic study comparing SB4 and etanercept reference product (Enbrel®) in healthy subjects
Impact of patient characteristics on the pharmacokinetics of corifollitropin alfa during controlled ovarian stimulation
Influence of chronic kidney disease and haemodialysis treatment on pharmacokinetics of nebivolol enantiomers
Population pharmacokinetic/pharmacodynamic modelling of the effects of axomadol and its O-demethyl metabolite on pupil diameter and nociception in healthy subjects
Pharmacokinetics and pharmacodynamics of multiple doses of BG00010, a neurotrophic factor with anti-hyperalgesic effects, in patients with sciatica
Population pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody
A phase I pharmacokinetics trial comparing PF-05280586 (a potential biosimilar) and rituximab in patients with active rheumatoid arthritis
Safety, pharmacokinetics and pharmacodynamics of GLPG0974, a potent and selective FFA2 antagonist, in healthy male subjects
High melphalan exposure is associated with improved overall survival in myeloma patients receiving high dose melphalan and autologous transplantation
Therapeutic protein–drug interaction assessment for daclizumab high-yield process in patients with multiple sclerosis using a cocktail approach
Cholesterol trials and mortality
Development of a population pharmacokinetic–pharmacodynamic model of a single bolus dose of unfractionated heparin in paediatric patients
The impact of genetic polymorphisms on the pharmacokinetics of efavirenz in African children
Safety, tolerability and pharmacokinetic properties of coadministered azithromycin and piperaquine in pregnant Papua New Guinean women
Characteristics and follow-up of postmarketing studies of conditionally authorized medicines in the EU
Exploring genetic and non-genetic risk factors for delayed graft function, acute and subclinical rejection in renal transplant recipients
Risk of acute and serious liver injury associated to nimesulide and other NSAIDs: data from drug-induced liver injury case–control study in Italy
The antipsychotic story: changes in prescriptions and overdose without better safety
Twenty-five years of prescription opioid use in Australia: a whole-of-population analysis using pharmaceutical claims
A scoping review of studies comparing the medication event monitoring system (MEMS) with alternative methods for measuring medication adherence
A ‘SMART’ way to determine treatment goals in pharmacotherapy education
The association between non-vitamin K antagonist oral anticoagulants and gastrointestinal bleeding: a meta-analysis of observational studies
The placebo response of injectable GLP-1 receptor agonists vs . oral DPP-4 inhibitors and SGLT-2 inhibitors: a systematic review and meta-analysis
Efficacy and safety of prophylactic levetiracetam in supratentorial brain tumour surgery: a systematic review and meta-analysis
Pharmacokinetics of rosuvastatin in 30 healthy Zimbabwean individuals of African ancestry