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Issue highlights
When less is more – efficacy with less toxicity at the ED50
Efficacy of olanzapine for the prophylaxis of chemotherapy‐induced nausea and vomiting : a meta‐analysis
Effect of ezetimibe on plasma adipokines : a systematic review and meta‐analysis
Psychotropics and weak opioid analgesics in plasma samples of older hip fracture patients – detection frequencies and consistency with drug records
Pharmacokinetics, safety, tolerability and immunogenicity of FKB327, a new biosimilar medicine of adalimumab/Humira, in healthy subjects
Remote ischaemic preconditioning suppresses endogenous plasma nitrite during ischaemia–reperfusion : a randomized controlled crossover pilot study
Investigation of the predictive validity of laser‐EPs in normal, UVB‐inflamed and capsaicin‐irritated skin with four analgesic compounds in healthy volunteers
Bronchopulmonary pharmacokinetics of (R)‐salbutamol and (S)‐salbutamol enantiomers in pulmonary epithelial lining fluid and lung tissue of horses
Pharmacokinetics of obinutuzumab in Chinese patients with B‐cell lymphomas
The CYP3A biomarker 4β‐hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation
Pharmacokinetics and pharmacodynamics of single doses of rivaroxaban in obese patients prior to and after bariatric surgery
Exposure‐response analysis after subcutaneous administration of RBP‐7000, a once‐a‐month long‐acting Atrigel formulation of risperidone
Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol‐containing oral contraceptive in healthy adult women
The impact of CES1 genotypes on the pharmacokinetics of methylphenidate in healthy Danish subjects
Multicompartment compliance aids in the community : the prevalence of potentially inappropriate medications
GPs' perspectives on prescribing for older people in primary care : a qualitative study
Safety profile of the direct oral anticoagulants : an analysis of the WHO database of adverse drug reactions
Identification of cellular targets involved in cardiac failure caused by PKI in oncology : an approach combining pharmacovigilance and pharmacodynamics
Comparative cardiovascular risks of dipeptidyl peptidase 4 inhibitors with other second‐ and third‐line antidiabetic drugs in patients with type 2 diabetes
Effect of type 2 diabetes mellitus on the pharmacokinetics and transplacental transfer of nifedipine in hypertensive pregnant women
Interdisciplinary pharmacometrics linking oseltamivir pharmacology, influenza epidemiology and health economics to inform antiviral use in pandemics
Affordable orphan drugs : a role for not‐for‐profit organizations