An alternative intermittent eltrombopag dosing protocol for the treatment of chronic immune thrombocytopenia
Medicinal cannabinoids in palliative care
Relative bioavailability of bedaquiline tablets suspended in water: Implications for dosing in children
The ‘top 100’ drugs and classes in England: an updated ‘starter formulary’ for trainee prescribers
Coadministration of probenecid and cimetidine with mirogabalin in healthy subjects: A phase 1, randomized, open-label, drug–drug interaction study
Pharmacokinetics, metabolism and safety of deuterated L-DOPA (SD-1077)/carbidopa compared to L-DOPA/carbidopa following single oral dose administration in healthy subjects
Increased risk of all-cause mortality associated with domperidone use in Parkinson's patients: a population-based cohort study in the UK
MEDI0382, a GLP-1/glucagon receptor dual agonist, meets safety and tolerability endpoints in a single-dose, healthy-subject, randomized, Phase 1 study
Mycophenolic acid concentrations in peripheral blood mononuclear cells are associated with the incidence of rejection in renal transplant recipients
The pharmacokinetics and the pharmacodynamics of cannabinoids
Effect of single and multiple doses of elobixibat, an ileal bile acid transporter inhibitor, on chronic constipation: A randomized controlled trial
Lopinavir/ritonavir treatment increases the placental transfer of bupivacaine enantiomers in human immunodeficiency virus-infected pregnant women
Reply to ‘The easy misuse of antidepressants during pregnancy is depressing’
Can doctors identify older patients at risk of medication harm following hospital discharge? A multicentre prospective study in the UK
Cannabis contaminants: sources, distribution, human toxicity and pharmacologic effects
Effect of tildrakizumab (MK-3222), a high affinity, selective anti-IL23p19 monoclonal antibody, on cytochrome P450 metabolism in subjects with moderate to severe psoriasis
A pharmacokinetics phase 1 bioequivalence study of the trastuzumab biosimilar MYL-1401O vs. EU-trastuzumab and US-trastuzumab
New-onset epilepsy in the elderly
Detecting a potential safety signal of antidepressants and type 2 diabetes: a pharmacovigilance-pharmacodynamic study
A comparative pharmacokinetic study of DRL_BZ, a candidate biosimilar of bevacizumab, with Avastin® (EU and US) in healthy male subjects
The easy misuse of antidepressants during pregnancy is depressing
Prescription patterns of angiotensin-converting enzyme inhibitors for various indications: A UK population-based study
Long-term adverse effects of paracetamol – a review
A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition
New drug controls and reduced hospital presentations due to novel psychoactive substances in Edinburgh
Total flucloxacillin plasma concentrations poorly reflect unbound concentrations in hospitalized patients with Staphylococcus aureus bacteraemia
A systematic literature review of the human skin microbiome as biomarker for dermatological drug development
The challenges of ‘medical cannabis’ and mental health: a clinical perspective
Incidence and risk factors of major bleeding following major orthopaedic surgery with fondaparinux thromboprophylaxis. A time-to-event analysis
In vivo affinity and target engagement in skin and blood in a first-time-in-human study of an anti-oncostatin M monoclonal antibody
Proton pump inhibitors and Raynaud's phenomenon: is there a link?
The pharmacokinetics, pharmacodynamics and tolerability of PUR0200, a novel tiotropium formulation, in chronic obstructive pulmonary disease
Interaction between ABCG2 421C>A polymorphism and valproate in their effects on steady-state disposition of lamotrigine in adults with epilepsy
Comparison of the Cockcroft–Gault, MDRD and CKD-EPI equations for estimating ganciclovir clearance
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials
Reply to ‘Comment on ‘Genotype-guided warfarin dosing versus conventional dosing strategies: a systematic review and meta-analysis of randomized clinical trials’ by Tse et al.’
Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study
Use of antipsychotics and risk of breast cancer: a Danish nationwide case–control study
Evaluation of accuracy of IHI Trigger Tool in identifying adverse drug events: a prospective observational study
Evaluation of a pharmacokinetic–pharmacodynamic model for hypouricaemic effects of febuxostat using datasets obtained from real-world patients
Dipeptidyl peptidase-4 inhibitor use is associated with decreased risk of fracture in patients with type 2 diabetes: a population-based cohort study
The use of complementary and alternative medicines during breastfeeding: results from the Herbal supplements in Breastfeeding InvesTigation (HaBIT) study
Safety, tolerability and pharmacokinetics/pharmacodynamics of the adrenomedullin antibody adrecizumab in a first-in-human study and during experimental human endotoxaemia in healthy subjects
Response to ‘Comment on ‘Measuring the impact of medicines regulatory interventions – systematic review and methodological considerations’ by Goedecke et al.’
Adverse effects of a single dose of gentamicin
Patient-reported outcome instruments that evaluate adherence behaviours in adults with asthma: a systematic review of measurement properties
Pharmacokinetics and C-reactive protein modelling of anti-interleukin-6 antibody (PF-04236921) in healthy volunteers and patients with autoimmune disease
A multiple treatment comparison meta-analysis of monoamine oxidase type B inhibitors for Parkinson's disease
Comment on ‘Measuring the impact of medicines regulatory interventions – systematic review and methodological considerations’ by Goedecke et al.
Genotype-guided warfarin dosing vs. conventional dosing strategies: a systematic review and meta-analysis of randomized controlled trials
Pharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open-label clinical trial
Patient involvement is essential in identifying drug-related problems
Gestational changes in buprenorphine exposure: A physiologically-based pharmacokinetic analysis
The analgesic efficacy and pharmacokinetics of epidural oxycodone after gynaecological laparotomy: a randomized, double-blind, double-dummy comparison with intravenous administration
Optimization of a drug transporter probe cocktail: potential screening tool for transporter-mediated drug–drug interactions
Stakeholders' views and experiences of pharmacist prescribing: a systematic review
Physiologically-based pharmacokinetic model of vaginally administered dapivirine ring and film formulations
Moderate correlation between systemic IL-6 responses and CRP with trough concentrations of voriconazole
The UK's Life Sciences Strategy: opportunities for clinical pharmacology
High exposure compared with standard exposure to metoclopramide associated with a higher risk of parkinsonism: a nationwide population-based cohort study
Appropriateness of oral anticoagulant therapy prescription and its associated factors in hospitalized older people with atrial fibrillation
Statin use associated with lower risk of epilepsy after intracranial haemorrhage: A population-based cohort study
Pharmacokinetics of cefuroxime in infants and neonates undergoing cardiac surgery
Gaps in predicting clinical doses for cannabinoids therapy: Overview of issues for pharmacokinetics and pharmacodynamics modelling
Comment on ‘Genotype-guided warfarin dosing versus conventional dosing strategies: a systematic review and meta-analysis of randomized clinical trials’ by Tse et al.
Identifying signals of interest when screening for drug-outcome associations in health care data
Cannabis, from plant to pill
‘Massive’ metformin overdose