Research Snippets
Traditional therapies in the management of moderate to severe chronic plaque psoriasis
Bone marrow cells differentiate into wound myofibroblasts and accelerate the healing of wounds with exposed bones when combined with an occlusive dressing
Interferon-γ is a potent inducer of catagen-like changes in cultured human anagen hair follicles
Human hair shape is programmed from the bulb
Conditioned medium from keloid keratinocyte/keloid fibroblast coculture induces contraction of fibroblast-populated collagen lattices
The lack of significant changes in scalp hair follicle density with advancing age
Increased activity of plasma and tissue kallikreins, plasma kininase II and salivary kallikrein in pemphigus foliaceus (fogo selvagem)
A mutation in SART3 gene in a Chinese pedigree with disseminated superficial actinic porokeratosis
Prevention of amputation caused by rheumatic diseases following a novel therapy of exposing bone marrow, occlusive dressing and subsequent epidermal grafting
Desmoplastic malignant melanoma
Dysplastic naevus vs. in situ melanoma
Circulating vascular endothelial growth factor in cutaneous malignant melanoma
The expression of cytotoxic mediators is altered in mononuclear cells of patients with melanoma and increased by interferon-α treatment
Effects of ultraviolet B irradiation, proinflammatory cytokines and raised extracellular calcium concentration on the expression of ATP2A2 and ATP2C1
Sequential application of cold and sodium lauryl sulphate decreases irritation and barrier disruption in vivo in humans
Simultaneous sodium lauryl sulphate testing improves the diagnostic validity of allergic patch tests. Results from a prospective multicentre study of the German Contact Dermatitis Research Group (Deutsche Kontaktallergie-Gruppe, DKG)
Expression of matrix metalloproteinase (MMP)-7 and MMP-13 and loss of MMP-19 and p16 are associated with malignant progression in chronic wounds
Clinical patterns of cutaneous nontuberculous mycobacterial infections
Validation of the International Study of Asthma and Allergies in Children (ISAAC) and U.K. criteria for atopic eczema in Ethiopian children
Risk factors for atopic dermatitis in New Zealand children at 3·5 years of age
Comparison of the 308-nm excimer laser and a 308-nm excimer lamp with 311-nm narrowband ultraviolet B in the treatment of psoriasis
The photocarcinogenic risk of narrowband UVB (TL-01) phototherapy
Treatment of psoriasis with topical sirolimus
Photodynamic therapy with topical methyl aminolaevulinate for ‘difficult-to-treat’ basal cell carcinoma
Salt sensitivity of blood pressure in patients with psoriasis on ciclosporin therapy
Modern external beam radiation therapy for refractory dissecting cellulitis of the scalp
Acute generalized exanthematous pustulosis induced by the antifungal terbinafine
Chronic actinic dermatitis treated with mycophenolate mofetil
Cutaneous collision tumour (melanocytic naevus, basal cell carcinoma, seborrhoeic keratosis)
Human sealpox resulting from a seal bite
Transition of pityriasis lichenoides et varioliformis acuta to febrile ulceronecrotic Mucha–Habermann disease is associated with elevated serum tumour necrosis factor-α
A severe case of pachyonychia congenita type I due to a novel proline mutation in keratin 6a
Photodynamic therapy using aminolaevulinic acid does not lead to clinical improvement in hidradenitis suppurativa
An insertion-deletion mutation in keratin 9 in three Chinese families with epidermolytic palmoplantar keratoderma
Serum levels of anti-agalactosyl IgG antibodies in mixed connective tissue disease
Successful treatment of pruritus with topical tacrolimus in a patient with primary biliary cirrhosis
Chronic anal ulceration due to nicorandil
Ciclosporin in psoriasis consensus statement
Ciclosporin in psoriasis consensus statement
Weekly low-dose docetaxel in the treatment of lung metastases from angiosarcoma of the head
A Japanese case of naevoid basal cell carcinoma syndrome associated with segmental vitiligo
Interstitial granulomatous dermatitis with plaques associated with antiphospholipid syndrome
Hailey–Hailey disease responsive to topical calcitriol
U.S. experience of immunomodulators in the treatment of psoriasis
U.S. experience of immunomodulators in the treatment of psoriasis
Parvovirus B19 and systemic sclerosis
Malignant lymphoma presenting as cutaneous granulomatous vasculitis
Xylitol as a causative agent of oral erosive eczema
Surgery for basal cell carcinoma
Surgery for basal cell carcinoma
Has acne increased? Prevalence of acne history among university students between 1948 and 1968. The Glasgow Alumni Cohort Study
On the possible relationship between staphylococcal superantigens and increased Vβ5·1 usage in cutaneous T-cell lymphoma
On the possible relationship between staphylococcal superantigens and increased Vβ5·1 usage in cutaneous T-cell lymphoma
Rook's Textbook Of Dermatology (2004) Seventh Edition. Eds Tony Burns, Stephen Breathnach, Neil Cox, Christopher Griffiths. Blackwell Publishing, Oxford. Hardback. ISBN 0632064293.
News and Notices
Downregulation of desmoplakin by RNA interference in HaCaT cells results in increased cellular proliferation
Laminin α3
Elucidation of connexin31 as a regulator of epidermal differentiation and tissue homeostasis
Functional effects of pachyonychia congenita type I mutations on keratinocyte migration and proliferation
Tight junction claudin expression and the effect of exogenous TNFα exposure
Melanocortin 1 Receptor Genotype and phaeomelanin/ eumelanin ratio in untanned Caucasian skin
Inhibition of calcium-independent phospholipase A impairs lysophosphatidic acid- induced calcium entry in keratinocytes
Dithranol induces cytochrome c release, caspase 3 activation and apoptosis in human keratinocytes
Impaired Langerhans cell migration in psoriasis
Novel autoantigens in the proteome of psoriatic epidermis
VEGF-A induced psoriasiform inflammation is ameliorated by blockade of VEGF receptor-3
IgGs reactive with proteins secreted by Streptococcus pyogenes are more abundant in serum from patients with chronic plaque psoriasis than healthy controls
The effects of TL01 phototherapy on UVB-induced Langerhans' cell, CD11b+ and iC3b+ cell trafficking in polymorphic light eruption (PLE)
Direct real-time electrochemical measurement and flow cytometry of UVA induced oxidative stress and its perturbation by mitochondrial electron transport chain inhibitors
Conjugated linoleic acids exhibit photoprotective properties, reducing UVR-induced IL-8 and PGE2 in human skin cells
UVA-induced changes in DNA 6-TG and the development of organ transplant associated cutaneous malignancies
Contribution of cutaneous interleukin-10 to the polarisation of immune responses to chemical contact and respiratory allergens
TRANCE and its receptors TRANCE-R and OPG are expressed in human epidermis and regulate Langerhans' cell longevity
Investigation of Der P 1-peptide specific T cell responses in individuals with severe atopic dermatitis
A novel antimicrobial photodynamic approach to treat chronic ulcers
Development of preimplantation genetic diagnosis for Hallopeau-Siemens recessive dystrophic epidermolysis bullosa
Disruption of stratum corneum by microfabricated microneedles for gene delivery from hydrogels
The Human forkhead transcription factor FOXM1B enhances DNA repair and suppresses UVB-induced apoptosis
Mechanisms of migration and invasion of squamous cell carcinoma in an in vitro model of squamous cell carcinogenesis
Increased Axl expression in invasive squamous cell carcinoma
Gli1 co-operates with EGFR signalling to induce a neuronal phenotype in keratinocytes
The effects of TL-01 phototherapy on erythema and provocation responses in polymorphic light eruption (PLE)
Computational prediction of cryptic splicing mutations in the COL7A1 gene in dystrophic epidermolysis bullosa
Missense FH mutations in multiple cutaneous and uterine leiomyomatosis and renal cell cancer
Inducible, conditional PTEN knockout and fos activation re-programmes keratinocyte differentiation, disrupts cell cycle and elicits keratoacanthoma-like lesions but not malignant conversion
Generation of stable knockdown in keratinocyte cell lines using retrovirus-mediated RNA interference
Microneedle facilitated gene delivery to human skin
Autoantibodies to basement membrane proteins BP180 and BP230 are commonly detected by immunoblot analysis in normal controls
Nitric oxide suppression of apoptosis in human skin following UV irradiation
Itching and healing
Investigation of Varicella Zoster virus-specific T cell responses
Phototesting in the Smith-Lemli-Opitz syndrome confirms sensitivity to UVA
Analysis of a single nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) in patients with vitiligo
The effect of UVA1, UVB and solar simulated radiation (SSR) on p53 activation and p21Waf1/Cip1
Apolipoprotein E (ApoE) single nucleotide polymorphisms (SNPs) and acitretin therapy in psoriasis
An extended fibrillin assay for assessment of ‘cosmetic’ antiageing products
Polymorphic light eruption is characterised by a partial failure of ultraviolet-induced immunosuppression
Analysis of asthma and high serum IgE associated haplotypes in atopic dermatitis (AD)
Could skin ultrasound improve melanoma yield in dermatology clinics?
Determination of eumelanin and pheomelanin concentrations in human epidermis before and after irradiation with UVB
LEKTI is required for skin barrier integrity and acts via the PAR-2 signalling pathway
Characterisation of night-to-night variation of disease activity in children with atopic dermatitis using digital limb-worn accelerometers
Can dietary furocoumarin ingestion enhance the erythemal response during high dose UVA1 therapy?
What determines the magnitude of tanning?
Identification of Fel d 1 specific CD8+ T cells in cat allergic and non-atopic individuals
Impact of polymorphic light eruption on quality of life across four seasons and at a range of latitudes in Europe
Variation in skin thickness may explain some of the within person variation in ultraviolet radiation induced erythema at different body sites
A comparison of two methods of measuring facultative pigmentation (tanning) that nullify the influence of changes in blood flow
The study of Serum and Glucocorticoid dependent kinases (SGKs) signalling with response to environmental stimuli
Evidence for a key role of Connexin 26 in early epidermal differentiation
Mechanisms of drug processing and presentation in cutaneous immune responses to phenytoin
Differential effects of chemical contact and respiratory sensitizers on Langerhans cell (LC) migration and maturation
The expression of early markers of adipocyte differentiation in sebaceous gland cells
Novel in vitro modelling of basal cell carcinoma
Melanocyte and keratinocyte culture on plasma polymers for the treatment of patients with vitiligo
Expression of Notch receptors during terminal differentiation of keratinocytes
Photoactivated platinum(IV) anticancer complexes
Chromosomal abnormalities in vulval intraepithelial neoplasia - influence on response to medical treatment