Research Snippets
Psoriasis and papillomaviruses
Stratum corneum RNA levels are diagnostic for melanoma
Spatial variation in incidence of nonmelanoma skin cancers
Methotrexate or fumarates: which is the best oral treatment for psoriasis?
Basal cell carcinoma: cell of origin, cancer stem cell hypothesis and stem cell markers
Review of the 90th Annual Meeting of the British Association of Dermatologists, 6–8 July 2010, Manchester, U.K.
CXCL10 reduces melanoma proliferation and invasiveness in vitro and in vivo
Vitamin D: a novel therapeutic approach for keloid, an in vitro analysis
Fingerprint maintenance, a new dermatoglyphic mechanism
Prognostic value and clinical significance of halo naevi regarding vitiligo
Depletion of antigen-presenting cells by clodronate liposomes reverses the psoriatic skin phenotype in KC-Tie2 mice
Noninvasive cutaneous blood flow as a response predictor for visible light therapy on segmental vitiligo: a prospective pilot study
Changes in the nail unit in patients with secondary lymphoedema identified using clinical, dermoscopic and ultrasound examination
Marked differences in Betapapillomavirus DNA and antibody prevalence between patients with psoriasis and those with atopic dermatitis
Frequencies of BRAF and NRAS mutations are different in histological types and sites of origin of cutaneous melanoma: a meta-analysis
Seven-point checklist of dermoscopy revisited
Filaggrin polymorphism P478S, IgE level, and atopic phenotypes
Noninvasive genomic detection of melanoma
How to quantify skin impairment in primary and secondary prevention? HEROS: a proposal of a h and e czema sco r e for o ccupational s creenings
Polo-like kinase 1 (Plk1) in cutaneous T-cell lymphoma
Geographical, urban/rural and socioeconomic variations in nonmelanoma skin cancer incidence: a population-based study in Ireland
Parental sun-protective regimens and prevalence of common melanocytic naevi among 7-year-old children in Sweden: changes over a 5-year period
Narrowband ultraviolet B inhibits innate cytosolic double-stranded RNA receptors in psoriatic skin and keratinocytes
An overview analysis of the time people spend outdoors
Fumarates vs. methotrexate in moderate to severe chronic plaque psoriasis: a multicentre prospective randomized controlled clinical trial
Cardiovascular safety of ustekinumab in patients with moderate to severe psoriasis: results of integrated analyses of data from phase II and III clinical studies
Absence of BRAF and HRAS mutations in eruptive Spitz naevi
The unique combination of dermatological and ocular phenotypes in Alström syndrome: severe presentation, early onset and two novel ALMS1 mutations
Compliance with indoor tanning advertising regulations in France
Detection of antibodies to epidermal transglutaminase but not tissue transglutaminase in Japanese patients with dermatitis herpetiformis
Recurrent bullous erythema multiforme treated with topical tacrolimus 0·1% ointment
Dramatic response to topical timolol lotion of a large hemifacial infantile haemangioma associated with PHACE syndrome
Local anaesthetic preparation in dermatological surgery: a labour- and time-efficient approach
No major role for glutathione S -transferase gene polymorphisms in sensitization to para -phenylenediamine and other xenobiotics: a study of association and a meta-analysis
Treatment of cutaneous sarcoid with topical gel psoralen and ultraviolet A
Comments on the British Association of Dermatologists guidelines for the management of lichen sclerosus
Bath psoralen plus ultraviolet A for hidradenitis suppurativa: a review of 13 patients
Incidence of cancer in the context of atopic dermatitis
Incidence of cancer in the context of atopic dermatitis: reply from authors
News and Notices
Monitoring the antibody repertoire of melanoma patients harbours the potential to identify novel treatments for cancer
Evidence for an immunosuppressive role by peritumoral regulatory T cells from human cutaneous squamous cell carcinomas
IL-22 is a potential therapeutic target in psoriasis
IL-17 influences expression of genes associated with barrier function in keratinocytes
Variation in the development of phenotype in filaggrinde-ficiency: a murine model of atopic dermatitis
Cutaneous antimicrobial peptides are induced in leprosy Type 1 reaction and suppressed by corticosteroids
Clinical relevance of pro-inflammatory skin homing CLA+ Vγ9Vδ2 T cells in psoriasis
Difference of epidermal antigen presenting cells in clinically normal skin of patients of atopic dermatitis with and without filaggrin mutations
In vitro modelling of basal cell carcinoma reveals a novel PTCH1-GLI1 signalling axis that is independent of SMOOTHENED in human keratinocytes
Identification of C20orf20 as a driver of cutaneous squamous cell carcinoma: a potential role for histone acetyltransferase activity in tumour progression
Axl plays a role in cell adhesion and ‘stemness’ in cutaneous SCC
Role of defective autophagy in melanoma development and progression: implication of oncogenic B-RAF signalling
Understanding the tumour-suppressing role of rapamycin in epidermis
IgE immunotherapy of solid tumours: a novel model targeting folate receptor α (FRα)-positive carcinomas with MOv18 IgE
Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling in vivo
Photoprotective properties of endogenous urocanic acid in human skin
Oxidative stress in human melanoma skin cells and its relationship with mitochondrial DNA damage and pigmentation
Photodynamic therapy modulates production of transforming growth factor (TGF)-β in association with improved healing in excisional wounds of human skin
The differential genetic effects of therapeutic UVB in psoriatic epidermis
Expression of LOXL1 in intrinsically aged and photoaged skin
Dephosphorlyation of cJun is required for claudin expression and tight junction formation during epidermal barrier acquisition
Egln3 as a key factor of HIF activity in epidermal keratinocytes
K1/K10 filaments are dispensable for epidermal barrier formation
Establishing the role of BPAG1-e in hemidesmosomal integrity and keratinocyte cell biology
iASPP mediates regulation of autophagy in keratinocytes
Skin-targeted inhibition of PPARβ/δ by selective antagonists to treat PPARβ/δ - mediated psoriasis like skin disease in vivo
Differential regulation of melanogenesis and melanin transfer by bone morphogenetic proteins in human skin
Controlled switching between states of epithelial proliferation and apoptosis in a mathematical model of the human hair cycle
Genetic and cellular evidence for a key role for a protease inhibitor in desmosomal adhesion
Heparanase genotype is associated with chronic plaque psoriasis and disease severity
Loss of organisation in CYLD defective tumours is associated with reduced DKK2 expression
Epigenetic dysregulation of novel candidate genes in malignant melanoma
Cx31 and AP1S1: evidence for interaction and a common molecular link with erythrokeratoderma
NCSTN and PSENEN mutations in familial hidradenitis suppurativa (acne inversa)
Autoantibodies against tyrosine hydroxylase in patients with non-segmental (generalised) vitiligo
Functional characterization of the regulatory mechanisms controlling HLA-C expression in psoriasis
HIV-1 escapes from BST-2/tetherin restriction in dendritic cells
Quantitative multicolour super-resolution microscopy reveals tetherin HIV-1 interaction
The IL23R R381Q gene variant protects against psoriasis by impairing IL-23-induced STAT-3 phosphorylation and IL-17A production in human Th17 cells
A multiparameter flow cytometry platform for immunological biomarker discovery in psoriasis
An investigation of the role of interleukin-1β in Langerhans' cell function in aged individuals
Impaired Langerhans' cell migration in an ex vivo psoriasis model
Suppressor of cytokine signaling (SOCS)-3 in the pathogenesis of atopic dermatitis
Definition of a peripheral lymphocyte subset expressing KIR2DL1+ receptors in psoriasis
Rapid diagnostic tests in the management of severe drug hypersensitivity
Vitamin D3 modulates the pro-inflammatory cytokine production by human Langerhans cells
The immunoregulatory role of B lymphocyte populations in malignant melanoma
Investigating anti-HMW-MAA IgG and anti-HMW-MAA IgE antibodies: a new approach in immunotherapy of melanoma
Pre-clinical mouse models of human skin transplant rejection, skin immune cell migration, and human melanoma xenografts for the in vivo assessment of novel immunotherapies
The role of TLR receptors in acne
The role of transforming growth factor beta in light induced resolution of acne vulgaris
Do epidermal melanocytes contribute to the erythema response in human skin post-UVB irradiation?
All- trans retinoic acid influences the macromolecular structure of fibrillin microfibrils
Implications of using ROS sensitive probes in studies of UVA induced ROS in skin cells
The action spectrum of UVR-induced damage within an 11 kb segment of mitochondrial DNA in human skin cells
UVA1 induces cyclobutane pyrimidine dimers in vivo
Differences in microRNA-34a responses following exposure to ultraviolet radiation and ionising radiation
The role, mechanism and protective effects of dietary antioxidants in human skin subjected to inducers of oxidative stress
Ultraviolet-B irradiation modulates tight junction protein expression in cultured primary keratinocytes
ARNT deficiency leads to reduced HDAC activity, suppression of EGFR/ERK pathway and defects in epidermal differentiation
Cis -urocanic acid modulates claudin-1 expression and tight junction function in human keratinocytes
L. reuteri can inhibit the cytotoxic effects of S. aureus on keratinocytes in vitro
Thyroid stimulating hormone receptor (TSHR) signalling as the underlying cause of skin disease associated with thyroid dysfunction
Reduced expression of several actin-associated focal adhesion proteins in Kindler syndrome keratinocytes harbouring FERMT1 mutations
Myosin Light Chain Kinase, a tight junction associated enzyme, is regulated by IL-1β in human keratinocytes
Epidermal expression patterns of HIF-α splice variants and their differential regulation by hypoxia
Gram positive bacterial cell wall components have different effects on wild type and mutant connexin 26 hemi channel activity and subsequent cytokine release in keratinocytes
Beta-defensin (hBD2) protects keratinocytes from the destructive potential of Staphylococcus secreted proteases
NFκB signalling and STAT3 localisation are altered in an in vitro model of lamellar ichthyosis
A systematic investigation of autoimmune loci in early onset psoriasis confirms an association with IL-2/IL-21
Towards deciphering a gene signature of anagen vs catagen in human hair follicles
Using next-generation sequencing to identify novel disease genes
Schöpf-Schulz-Passarge syndrome resulting from a recurrent homozygous nonsense mutation, p.Cys107X, in WNT10A
Biomarkers of skin ageing using genome wide transcriptomics
Genome-wide expression profiling of the psoriatic transcriptome
Recessive epidermolytic palmoplantar keratoderma caused by a keratin 1 mutation
New and recurrent FERMT1 mutations in Kindler syndrome
Methylation profiling of cutaneous squamous cell carcinoma
Global analysis of transcription reveals BCSC-1 as a melanoma tumor suppressor that downregulates MITF
Microarray expression profiling identifies novel targets and pathways involved in cutaneous squamous cell carcinoma oncogenesis
The tumour suppressor PTCH1 regulates EGFR signalling in human keratinocytes: implications for the treatment of basal cell carcinoma
Skin carcinogenesis in Ras/fos/PTENnull transgenic mice reveals an activated AKT association with malignant progression but mTOR associates with papillomatogenesis/malignant conversion
Validation of the B1 bradykinin receptor as a potential therapeutic target in cutaneous squamous cell carcinoma
High resolution microarray analysis of vulval neoplasia reveals genetic differences between human papillomavirus-positive and negative tumours
Phospholipase C signalling in cutaneous squamous cell carcinoma
Senescence in human basal cell carcinoma
STAT3 as a potential substrate for protein tyrosine phosphatase receptor delta (PTPRD) in cutaneous squamous cell carcinoma
Role of Mcl-1 in the resistance of B-RAF mutated melanoma to autophagy
Are immunosuppressed patients at greater risk of Merkel cell polyomavirus in non-melanoma skin cancer?
Biomarkers of defective autophagy in melanoma
The association between cutaneous squamous cell carcinoma and beta papillomavirus seropositivity: a cohort study
Temporal trends in the incidence of invasive cutaneous melanoma by anatomic site in U.K., 1979–2006
Global resource of EczemA Trials (GREAT database)