MicroRNA profiling in Sezary syndrome
2-phenylacetylenesulphonamide induces p53-independent apoptosis of CLL cells via upregulation of the BH3 protein Noxa
WT1-TCR gene transfer into HSCs: a tumour immunotherapy model
Stromal cell-mediated drug resistance in acute myeloid leukaemia (AML) is attenuated by PI103, a dual inhibitor of Class I PI3-Kinase (PI3K) and mTOR
Dasatinib induces apoptosis of chronic lymphocytic leukaemia cells in vitro, and shows synergy with established and novel chemotherapeutic agents
CCN3, a novel growth inhibitory factor for chronic myeloid leukaemia
Pooled analysis of four pivotal studies of rivaroxaban for the prevention of venous thromboembolism after orthopaedic surgery
Persistent high factor VIII activity leading to increased thrombin generation
Thrombin generation is normal in most patients with cirrhosis despite a prolonged INR
Direct thrombin inhibitors, but not factor Xa inhibitors, enhance thrombin formation in human plasma by interaction with the thrombin-thrombomodulin-protein C system
Serum rituximab levels in TTP: the effect of plasma exchange and correlation with response to treatment
Outcomes of hepatitis C infection in a large haemophilia population
Effects of RNAi-mediated suppression of SDF-1 gene in bone marrow stromal cells on the co-cultured Jurkat cells
Identification of Huntingtin interacting protein 1 related (HIP1R) as a novel lymphoma autoantigen using antigen array profiling
FAM129C, a novel B cell protein, is downregulated during CD40L activation but not BCR stimulation
CD138 expression on circulating myeloma cells correlates with disease activity
Influence of variable tandem number repeats (VNTRs) in promoter region of thiopurine methyltransferase (TPMT) gene on enzyme activity: an Asian perspective
Complex activation of angiogenic signaling in chronic lymphocytic leukaemia: evidence from circulating angiogenic cytokines, association with prognostic markers and impact on clinical course
Elevated soluble endoglin (Scd105) is a novel adverse prognostic factor in chronic lymphocytic leukaemia
Defining a molecular signature for high hyperdiploid acute lymphoblastic leukaemia (ALL) in children using global gene expression profiling
Combined blockade of PI3-kinase and mTOR synergizes with gamma-secretase inhibitors to induce a high level of cell death in T-cell acute lymphoblastic leukaemia cells with activated Notch signalling
Expression of FOXP2 is up-regulated in lymphoid malignancies
ABCB1 (MDR-1) rs1045642 is associated with increased overall survival in plasma cell myeloma
Biallelic 13q14.3 deletion in patients with chronic lymphocytic leukaemia
Preliminary toxicity results from a phase II trial of CHOP (cyclophosphamide, doxorubicin, vincristine, prednisolone) chemotherapy with or without Bortezomib for mantle cell lymphoma in first relapse
A clinical audit of venous thromboprophylaxis in multiple myeloma
Kikuchi-Fujimoto disease co-existing with breast cancer metastases in axillary lymph nodes
Single arm phase II open label study of thalidomide in patients with refractory or relapsed diffuse large B cell lymphoma
Cost-effectiveness of pentostatin compared to cladribine in the management of hairy cell leukaemia in the UK
A novel immunophenotyping score discriminates mantle cell lymphoma from B cell chronic lymphocytic leukaemia
Validation of the mantle cell lymphoma international prognostic index (MIPI) in a non selected population of patients
Treatment outcomes of primary CNS lymphoma with IDARAM chemotherapy regime
An unusual form of myeloma relapse: transformation or a resistant clone ?
Ultra low dose thalidomide in myeloma revisited
How old is too old to receive intensive chemotherapy for diffuse large B-cell lymphoma (DLBCL) - single centre DGH experience
Rituximab in combination with CODOX-M/IVAC: toxicity and efficacy in 17 adults with non-HIV related B-cell non-Hodgkin lymphomas with > 95% proliferation index
A ten year audit of the management of diffuse large B-cell lymphoma in the elderly
Bortezomib, adriamycin and dexamethasone for patients with refractory and relapsed myeloma - results from the PAD (Ireland) study
Alemtuzumab administered by subcutaneous route is less effective than intravenous route for first line therapy of T-cell prolymphocytic leukaemia: results of a pilot study (UKCLL05)
Review of the clinical and laboratory features of germinal centre and activated B cell subtypes of diffuse large B cell lymphoma at presentation
The use of bortezomib in myeloma patients in a single centre following the implementation of NICE guidance
Intra-vitreal methotrexate leads to resolution of hypopyon secondary to chronic lymphocytic leukaemia / small lymphopcytic lymphoma
Detection of MPL W515L/K mutations in patients with primary myelofibrosis and essential thrombocythaemia
Abstract withdrawn.
pMHC arrays: analysis of T cell populations in myeloid leukaemia patients during treatment
Identification of a novel cancer-testis antigen as a target for the immunotherapy of acute myeloid leukaemia (AML)
Treatment resistance in chronic myeloid leukaemia and the role of kinase domain mutations
Changes in microRNA expression in acute myeloid leukaemia cell lines when treated with an inhibitory dose of 5-aza-2′-deoxycytidine, a DNA methylation inhibitor
The development of biomarker assays to assess clinical responses to rapamycin analogues
Establishment of a megakaryocyte culture system for studying the myeloproliferative disorders
Associations of FLT3, NPM1 and c-KIT aberrations in paediatric acute myelogeneous leukaemia
Tyrosine kinase and proteasome inhibition alter proteasome expression in BCR-ABL positive cell lines
Global methylation changes in acute myeloid leukaemia cell lines after treatment with a demethylating agent identifies candidate genes for investigation into restored expression
Modification of the standard eculizumab dose to successfully manage intravascular haemolysis breakthrough in patients with paroxysmal nocturnal haemoglobinuria
Successful pregnancy outcome in paroxysmal nocturnal haemoglobinuria on long term eculizumab
A single centre audit of vaccination rates in an adult population with sickle cell disease
Standards of care for adult patients with sickle cell disease in the United Kingdom
Codon 25/26(+T) beta-globin gene mutation, a rare beta 0- thalassemia variant without transfusion dependence
Initial assessment of children with sickle cell disease presenting to RMCH: does presenting neutrophil count aid diagnosis and correlate with severity of sickle cell crisis?
The effect of hydroxyurea therapy on pulmonary function in adults with sickle cell anaemia
Patient satisfaction in sickle cell disease
Application of MLPA and gap-PCR mapping to characterise a novel beta globin gene cluster deletion mutation in a family of Afghan ancestry
The use of Werkentin et al. scoring system to determine the appropriateness of HITT antibody testing in Northern Ireland
Evaluation of deep vein thrombosis (DVT) diagnostic strategy using combined D-dimer and strain gauge plethysmography(venometer)
An audit of the use of low-dose prothrombin complex concentrate in emergency reversal of oral anticoagulation
PreVent: an electronic protocol for the prevention of VTE in acute inpatients
Use of prothrombin complex concentrate - experience in a large tertiary care hospital
Segregation of type 1, type 3, and type 2N von Willebrand disease in three generations of an affected family
Establishment of an external quality assessment programme for users of activated clotting time
Reference ranges in thrombophilia screening
Clinical assessment and laboratory testing for heparin induced thrombocytopaenia (HIT); current practice amongst UK NEQAS (blood coagulation) participants
Detection of factor VIII inhibitors, a comparison of an inhibitor screening test and Bethesda assay in children with haemophilia A
Detection of dysfibrinogenaemia using the PT and APTT is dependent on reagent and coagulometer
A retrospective look at the out of hours requests for routine coagulation screens
Outpatient warfarin induction: an audit of two regimens used in a district general hospital
Practice in point of care INR testing-review of questionnaires from 2001, 2004 and 2007 of UK NEQAS participants
Thromboprophylaxis in medical patients
Improving specificity of laboratory testing of HITT in Northern Ireland
Identification of a pseudogene conversion in the von Willebrand factor gene as the cause of type 3 von Willebrand disease
Activated factor VII and activated prothrombin complex for reversal of the antihaemostatic effects of rivaroxaban in primates
The therapeutic potential of enhanced thrombolysis with rivaroxaban, an oral, direct factor Xa inhibitor, in patients with thrombosis
The use of inferior vena caval filters at Royal Cornwall Hospital NHS Trust
Monitoring platelet counts - post operative hip and knee replacements on prophylactic low molecular weight heparin (LMWH)
Repeated courses of low-dose rituximab may be effective and safe in chronic relapsing immune thrombocytopenic purpura (ITP)
Off-license use of recombinant factor VIIa: a single centre experience
Gastrointestinal bleeding due to angiodysplasia in patients with inherited platelet function disorders
Implementation of an electronic risk assessment tool with rule based recommendations for prevention of hospital acquired venous thromboembolism
A formula for predicting the maintenance dose of warfarin in patients started on a daily 5mg dose
Effects of rivaroxaban, a novel, oral, direct factor Xa inhibitor, on coagulation assays
A survey of venous thromboembolism (VTE) prevention practice in the UK
Effects of age, weight, gender and renal function in a pooled analysis of four phase III studies of rivaroxaban for the prevention of venous thromboembolism after major orthopaedic surgery
Usefulness of pretest clinical scores (‘4Ts’) and their correlation with the rapid ID-heparin / PF4 antibody testing for the diagnosis of heparin induced thrombocytopenia
Factor XIII deficiency: effective haemostasis despite treatment for the wrong diagnosis
Prospective study to evaluate the role of D-dimers in patients with moderate Wells clinical probability score
Thrombin generation - development of normal range for children
Circulating markers of arterial thrombosis and age-related maculopathy: a case-control study
Use and efficacy of prothrombin complex concentrate in the west of Scotland 2007-2008
Prospective study of initial management and long term outcome in a cohort of patients requiring urgent warfarin-reversal
Major cardiovascular disease in a child with antithrombin deficiency - type II heparin binding defect
Quality of life in patients over 60 with acute myeloid leukaemia on palliative care pathwaysF Cran, C Poynton, M Harness University of Wales Hospital, Cardiff, UK
Nilotinib in chronic myeloid leukaemia patients in chronic phase (CML-CP) with imatinib resistance or intolerance: follow-up results of a phase 2 study
Seven year follow-up of the International Randomized Study of Interferon Versus STI571 (IRIS) demonstrates durable efficacy and long-term safety of imatinib in patients (pts) with newly diagnosed chronic myeloid leukaemia in chronic phase (CML-CP)
The cost of treatment of acute myeloid leukaemia
Defining the landscape of resistance mutations in the context of modern treatment protocols for acute promyelocytic leukaemia
Favourable outcome for allogeneic haematopoietic transplant recipients requiring intensive therapy unit admission with improved survival following reduced intensity conditioning
Genomic breakpoint cloning and a functional assay of DNA topoisomerase II cleavage reveals translocation mechanism underlying formation of t (15;17) in epirubicin-related acute promyelocytic leukaemia
Home infusion of eculizumab: a survey of a unique model of drug delivery for patients in the NCG PNH service
The influence of VKORC1 and CYP2C9 genetic polymorphisms on early INR control in patients commencing warfarin
Minimal residual disease is a significant predictor of treatment failure in B lineage adult ALL: final results of the international trial UKALL XII:ECOG 2993
Erythropoietin synthesis is primarily regulated by the PHD2-HIF-2alpha-VHL axis as documented by HIF-2alpha associated familial erythrocytosis
NCRN CLL207 study of alemtuzumab consolidation in CLL: report of the planned interim analysis
Free fetal DNA, sex determination in haemophilia carriers
Sleep disordered breathing and transcranial Doppler in sickle cell anaemia
Post-remission MRD kinetics in children with acute lymphoblastic leukaemia receiving augmented BFM consolidation compared with other regimens: update of results of the Medical Research Council Trial UKALL2003
Anthracycline cardiotoxicity in children treated for acute myeloid leukaemia; experience in a single centre
Rituximab in children: experience of a regional paediatric bone marrow transplant unit
FLT3-ITD mutations as a prognostic factor in children with AML - experience in a uniformly treated, large, single centre cohort
National comparative audit of use of fresh frozen plasma (FFP) in adult patients (aged 16years or over)
Eculizumab reduces pulmonary hypertension through inhibition of haemolysis-associated nitric oxide consumption in patients with paroxysmal nocturnal haemoglobinuria
Serious Hazards of Transfusion (SHOT) reports relating to anti-D immunoglobulin
Association of estimated intake of dietary factors with clinical severity of sickle cell disease in an African-American paediatric cohort
Prevalence of genetic modulators and their effect on the phenotype of HbE- beta thalassaemia patients
Measurement of stem cell potency, assessment of acceptance limits for release criteria and prediction of umbilical cord blood engraftment
Successful use of pulsed methyl-prednisolone as an alternative to immunoglobulin (IVIg) in patients with chronic idiopathic thrombocytopenia (ITP), prior to elective surgery
Diagnosis and management of essential thrombocythemia in a district general hospital
IPF is inversely proportional to the platelet count and is highest among patients with ITP and acute leukaemia
Impact of early warning scoring system and ITU outreach teams on outcomes of haematology patients requiring admission to intensive care unit
Six months retrospective audit of Hickman line related bacteraemia in a district general hospital
Evaluation of training for malaria diagnosis in Africa and assessment of diagnostic competency using Internet based virtual slides prior to evaluation of a pilot virtual training programme for malaria diagnosis
An investigation into the clinical utility of a flow cytometric method of indicating infection using CD64 and CD11b
Immunophenotyping: Thames Valley Haemato-Molecular Diagnostic Service. A shift in emphasis? A detailed one-year audit
Progress with a pilot scheme for assessing quality and consistency of bone marrow aspirate reporting in the North Trent Haemato-Oncology Diagnostic Service
Thalidomide and lenalidomide to control gastrointestinal bleeding in hereditary haemorrhagic telangiectasia
An audit of coagulation tests requests in the Emergency Department of an average sized district general hospital and the development of an electronic version of restrictive ordering model to limit requests based on clinical indications
Audit of intravenous iron usage in the Ulster hospital
Evaluation of the validity of UK NEQAS Hb A2 data for the NHS sickle cell and thalassaemia screening programme
Use of intravenous immunoglobulin in the management of immune thrombocytopenic purpura: a review of 12 months clinical use in a single centre
Morphology Training Quality Assessment System (MTQAS)
Are monoclonal paraproteins followed up adequately?
Assessment of vitamin B12 testing over a 4 week period in the Mid-Western Regional Hospital, Limerick
Automated erythrocytapheresis in the acute management of newly diagnosed polycythaemia vera
Darbepoetin is more cost-effective than regular transfusion: a review of the use of erythropoietin in haematology patients
Systems biology analysis of the G0 → G1 commitment point of human primary T cells
Venous thromboembolism risk assessment: an audit of haematology in-patients at Derby Hospitals Foundation Trust, UK
Bacteraemia in a tertiary hemato-oncology center in 2008
An audit of blood cultures in acute leukaemia: changing patterns and practices
Digital morphology: a new UK NEQAS(H) scheme for Continuing Professional Development
Teaching practical laboratory skills in the 21st century
Inequity in access to bone marrow transplants: an examination of regional differences in haematopoietic stem cell activity between health authorities in South East England
The virtual slide; evaluation of three different methods for quality digital imaging for the UK NEQAS (H) digital morphology scheme
Association of insulin like growth factor-1 (IGF) and thyroid hormones in patients with acute leukaemia
Alteration in lipid profile in patients with chronic myeloid leukaemia before and after chemotherapy
FACS assessment of pCrKL/CrKL ratio at initial diagnosis is predictive of long term treatment outcome in chronic myeloid leukaemia (CML)
Utilisation of allogeneic transplantation in poor-risk acute myeloid leukaemia
V617F JAK2 mutation is associated with thrombo-embolic events in primary thrombocythaemia
BCR-ABL peptide boost vaccinations can maintain anti-BCR-ABL immune responses in chronic myeloid leukaemia (CML) patients
A retrospective analysis of chronic myeloid leukaemia (CML) in Papua New Guinea (PNG) 2001-2008, with prospective preliminary molecular analysis for BCR-ABL in preparation for the introduction of the Glivec International Patient Assistance Program (GIPAP).
A simple diagnostic test for MPL exon 10 mutations in myeloproliferative neoplasms
Safe and effective use of combination therapy with anagrelide and hydroxyurea in patients with chronic myeloproliferative disorders
A luminescent whole cell bacterial biosensor for rapid pre-screening of chemotherapy efficacy
Outcome of persistant CD7 positivity in AML
Successful routine cytogenetic analysis from trephine biopsy specimens following failure to aspirate bone marrow
Use of pegylated interferon as second-line therapy in patients with essential thrombocythaemia or polycythaemia vera who are refractory or intolerant to other agents
Absolute lymphocyte count (ALC) is a powerful predictor of outcome in patients with acute myeloid leukaemia (AML) receiving intensive chemotherapy
Hypereosinophilic syndromes (HESs): clinical presentation and variable clinical response - a case series
Peninsula Haematology Research Roadshow - an evaluation of study days in the Peninsula
Stem cell collection made easy!
Preparation through education
Extended role of the haematology clinical nurse specialist in a smaller NHS trust as ‘physician assistant’
A regional audit of essential thrombocythaemia: benefits, implications and future directions
Myeloid malignancies - CNS nurse or bereavement counsellor?
Shifting the Burden
Survey of patient's perception of a haemoglobinopathy service in the hospital and in the community: is there a need for the role of a clinical nurse specialist?
Cross-cultural translation of a disease specific quality of life tool for childhood haemophilia
Thiopurine methyltransferase screening in children with acute lymphoblastic leukaemia. Genotype or phenotype?
Paediatric haemophilia in Oxford, 1989-2008
Diagnostic review of children with presumed immune thrombocytopenic purpura in the greater manchester and lancashire region
A comparison of four measures of iron-deficient erythropoiesis in a paediatric population with a high incidence of iron deficiency
Red cell morphology according to iron status in young children
Bone mineral density in children with severe haemophilia receiving regular FVIII prophylaxis
Neurological complications of paediatric sickle cell anaemia in Wessex
A role for non invasive ventilation for acute chest syndrome in children: our experience
Thrombin generation potential in children with thrombocytopenia secondary to ITP
Neutrophil oxidative burst in response to chemical and bacterial stimulation in preterm infants and expression of adhesion molecules
PBSC harvesting in paediatrics: logistics and outcomes - the Oxford experience
Prophylaxis for severe protein C deficiency: a novel approach
Intravenous iron therapy: an effective alternative to transfusion in vascular and colorectal cancer patients
Transfusion in a medical setting guidelines and training may not be sufficient to ensure safe and appropriate practice. May to July 2008
Audit of red cell use in the hospitals in the South West and West Midland regions
Six year experience of intraoperative red cell salvage in one district general hospital
Paediatric blood transfusion: an audit of current countywide practice with Gloucestershire Hospitals NHS Foundation Trust
Serious Hazards of Transfusion (SHOT) near miss reporting
Out of hours transfusions
Is FFP still used to reverse warfarin anticoagulation?
Routine antenatal anti-D prophylaxis (RAADP) in RhD negative women. What is the best approach?
Red cell transfusion in haematology: can we reduce usage further?
Obstetric transfusion and iron survey (OTIS)
The design and implementation of a maximum blood-ordering schedule (MSBOS) for a tertiary paediatric cardiothoracic surgical unit
Use of ‘massive transfusion packs' at a major trauma centre
Audit of informed consent for blood transfusion of patients undergoing major cardiac procedures
A multidisciplinary approach to requesting irradiated blood products
Thrombin generation in children - pre and post platelet transfusion
Improvements in platelet transfusion practice at University Hospitals, Bristol has been brought about by sequential audits
Use of erythropoietin (EPO) in adult patients prior to elective major orthopaedics surgery to reduce exposure to allogeneic blood transfusion: a pilot study
Prognostic impact of serum ferritin concentration on survival following reduced intensity conditioned allogeneic haemopoietic stem cell transplantation
Abstract withdrawn.
Outcomes of 32 T-cell replete reduced intensity conditioning (RIC) matched sibling allografts for acute myeloid leukaemia: a single centre experience
The expression of receptors for the homeostatic cytokines IL-7 and IL-21 is reduced on T cells following autologous stem cell transplantation
Immune reconstitution two years or more post allogeneic haemopoietic stem cell transplantation
Oral posaconazole is safe and effective fungal prophylaxis in patients with abnormal liver function post HSCT
Increased morbidity and mortality in post allogeneic transplant parainfluenza virus 3 versus respiratory syncytial virus infection
Extracorporeal photopheresis for steroid-refractory chronic graft-versus host disease: lymphocyte yield and cell dose is not influenced by number of treatment cycles and yield was not associated with treatment efficacy
Cytotoxic T-cell response to the PASD1 protein in patients with diffuse large B-cell lymphoma
Ki-67 does not predict survival in newly-diagnosed mantle cell lymphoma treated with fludarabine and cyclophosphamide (FC) with or without rituximab (R)
Good response rates following second autologous transplantation after bortezomib-based re-induction therapy
Epigenetic code of primary human T cells during the first cell cycle
Audit of ABVD chemotherapy for Hodgkins lymphoma patients regardless of the absolute neutrophil count and without G-CSF; no treatment delays and optimal dose intensity