Amplification of MLL perturbs haematopoiesis and cooperates with MLL partial tandem duplication to induce acute myeloid leukaemia
Acquired factor XIII deficiency - an under investigated disorder
An open-label phase II study to investigate the safety and efficacy of rituximab plus chlorambucil in previously untreated patients with CD20-positive B-cell chronic lymphocytic leukaemia (CLL): On behalf of the NCRI CLL sub-group
Characterisation of a genetic disease modifier locus in patients with sickle cell anaemia
Efficacy of panobinostat in phase II study in patients with relapsed/refractory Hodgkin lymphoma (HL) after high-dose chemotherapy with autologous stem cell transplant
Gene- and microRNA- expression signatures of good prognosis in B-cell precursor acute lymphoblastic leukaemia
Clinical predictors of adverse outcome in VTE outpatients - the VERITY PUSH study
Identification of non-carrier mothers of patients with haemophilia A or B: Counselling implications for future offspring
Plasma factor VII a potential marker of pre-eclampsia
Anti-ADAMTS13 IgG antibody subclasses in thrombotic thrombocytopenic purpura and changes with rituximab therapy
Early coagulopathy is associated with increased mortality and re-bleeding in non-cirrhotics with acute upper gastrointestinal bleeding
Effectiveness of prophylactic treatment in preventing thromboembolic events in medical subgroups: A meta-analysis of randomised clinical trials
Performance assessment of newborn sickle screening in the UK
Over-expression of LIN28B is correlated with prognosis in juvenile myelomonocytic leukaemia patients and involves an additional mechanism of RAS-signalling pathway activation
Primary CNS lymphoma in children and adolescents: A descriptive analysis from the International Primary CNS Lymphoma Collaborative Group (IPCG)
Changes in paediatric anticoagulant care as a result of the introduction of an anticoagulant nurse practitioner
Sequential acquisition of BCR-ABL1 fusion and IKAROS deletion in Philadelphia chromosome positive ALL
Abstract withdrawn.
Terminal complement inhibitor eculizumab improves complement-mediated platelet consumption and thrombocytopenia in patients with paroxysmal nocturnal hemoglobinuria (PNH)
A prospective observational study evaluating changes in coagulation parameters in trauma admissions
Mechanisms for the shuttling of plasma non-transferrin-bound iron (NTBI) onto deferoxamine by deferiprone
Fetomaternal alloimmune thrombocytopenia (FMAIT) in the UK: A prospective national study of incidence and outcomes using obstetric, paediatric and laboratory reporting systems
Nocturnal haemoglobin oxygen saturation variability is associated with vitamin C deficiency in Tanzanian children with sickle cell anaemia
A spontaneous reduction of clone size in paroxysmal nocturnal haemoglobinuria patients treated with eculizumab for greater than 12 months
A comparison of rivaroxaban and fragmin prophylaxis after high risk orthopaedic surgery on thrombin generation test
Lower doses of prothrombin complex concentrate achieve emergency reversal of warfarin
Identification of deletion mutations in the factor VIII gene of affected males and female carriers of haemophilia A using multiplex ligation-dependent probe amplification (MLPA)
Heparin resistance and antithrombin deficiency
Implementation of British Committee for Standards in Haematology (BCSH) Guidelines: Data from two UK NEQAS (Blood Coagulation) questionnaires
Thrombotic thrombocytopenic purpura associated with statin therapy
WT1 peptide vaccination in poor risk adult AML patients induces WT1-specific immune responses: Results of a leukaemia research supported phase I clinical trial, WTPV-001
A Cre/Lox model of leukaemia initiation and maintenance
Refinement of cytogenetic classification in acute myeloid leukaemia: Determination of prognostic significance of rarer recurring chromosomal abnormalities amongst 5,876 younger adult patients treated in the UK Medical Research Council trials
The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukaemia is dependent on FLT3/ITD status
Non-cycling cells from acute myeloid leukaemia patients harbor the FLT3-ITD (FMS-like tyrosine kinase 3- internal tandem duplication) mutation and exhibit in vitro insensitivity to TKI258, a potent FLT3-directed inhibitor
The epigenetic therapies azacitidine and sodium valproate induce immune responses to the MAGE cancer testis antigen in patients with acute myeloid leukaemia achieving a complete remission
Large scale screening for DNA damage-induced transcription factors as potential targets for treatment of ATM/TP53 mutant CLL with p53 apoptotic defect
KIR genotype is associated with progression free and overall survival following autologous stem cell transplantation for multiple myeloma
Predicting clinical outcome in early stage chronic lymphocytic leukaemia (CLL): A multi-centre study of 1153 patients
Dual inhibition of phosphoinositide 3-kinase (PI3K) and mTOR signalling selectively induces apoptosis in multiple myeloma cells expressing the t(4;14) translocation
Achieving minimal residual disease (MRD) negativity in CLL is independently associated with improved progression-free and overall survival and is an appropriate end-point of therapy
HLA-mismatched unrelated donors are a viable alternate graft source for allogeneic transplantation following alemtuzumab-based reduced intensity conditioning
Arsenic trioxide and stem cell transplantation is an effective salvage therapy in patients with relapsed APL
Refractory anaemia with ringed sideroblasts (RARS) are characterized by a deregulation of iron related genes
EVI-1 oncogene expression predicts survival in chronic phase CML patients resistant to imatinib
Monoclonal gammopathy following allogeneic haematopoietic stem cell transplantation: A frequent finding associated with alemtuzumab T-cell depletion
Evidence of a cell-dose effect in extracorporeal photopheresis therapy of chronic graft versus-host disease
The impact of second generation tyrosine kinase inhibitors on the outcome of allogeneic stem cell transplantation for chronic myeloid leukaemia
Promoting a positive patient experience in haematology with the development of care pathways
UK Systemic Mastocytosis registry: Analysis of data on 95 cases
An audit to determine the patient's perspective of specialist nurses running myeloproliferative clinics
Erythropoietin-induced activation of Rho/ROCK/MLC2 in a model of tumourigenesis
Anticoagulant therapy: Staff training using e-learning. The West Suffolk Hospital NHS Trust experience
Ability of holotranscobalamin assay (Active B12) to detect severe cobalamin deficiency evidenced by high methylmalonic acid in the presence of high titre intrinsic factor antibody and false normal B12 results
Acute venous thrombosis treatment in pregnancy. A multi centre report from Iran over 6 years
Perinatal management of babies with haemophilia
Promoting warfarin safety in hospitalised patients: A multidisciplinary approach
Safe and effective evaluation of the international normalised ratio (INR) by point of care testing in patients on oral vitamin K antagonists prior to cardiac procedures
Establishing a nurse-led electronic thrombophilia service in a district hospital
Superficial venous thrombosis: Single-centre experience of management and outcomes
VerifyNow® P2Y12 assay for thienopyridine resistance: Single-centre experience
Review of all deaths due to pulmonary embolism (PE), identified at autopsy, over 12 months, within a large teaching hospital
The use of coagulation tests in the preoperative assessment of bleeding risk
Patients under 45 years of age attending a district general hospital outpatient deep vein thrombosis clinic: Characteristics and management
Outpatient diagnosis of deep vein thrombosis in pregnant women
Large scale snap-shot audits of venous thromboembolism (VTE) prophylaxis within an exemplar centre demonstrates very good application
Pre-operative fibrinogen level is predictive of perioperative bleeding
Audit of D-dimer levels in the diagnosis of venous thrombo-embolism
Audit of hospital-acquired thrombosis in a district general hospital
A retrospective, radiology audit of venous thromboembolism in all hospitalized adult patients, over a six month period, within a large teaching hospital
Levels of circulating microparticles in patients with gynaecological malignancy - a case-control study
Evaluation of the Multiplate® whole blood platelet aggregometer: normal ranges and diurnal variation assessed in healthy volunteers
Case report of a homozygous 20209C>T substitution in 3′ UTR of the prothrombin gene
Evaluation of an automated platelet-based assay of von Willebrand ristocetin cofactor activity
Nitric oxide indirect markers in mild and severe forms of pre-eclampsia
Increased plasma thrombomodulin levels in pre-eclampsia: Endothelial damage or renal insufficiencies?
Changes in fibrinolytic parameters in pre-eclampsia
Fibrinolytic markers in patients undergoing haemodialysis
Improving venous thromoboembolism prophylaxis in medical inpatients
Lemierre's Syndrome - the forgotten disease?
Thrombin generation: Diurnal variation of measured parameters during the working day
Use of an ADAMTS-13 activity ELISA kit to monitor treatment in a patient with congenital thrombotic thrombocytopenic purpura [TTP],
An audit of patients over age 90 attending the anticoagulant service at the University Hospital of South Manchester
A multiple cycle audit for improving thromboprophylaxis
The effect of exogenous antithrombin on measurement of anti-Xa activity
Heparin-induced thrombocytopenia: The 4Ts in ICU
A retrospective audit of extended low molecular weight heparin (LMWH) therapy in patients deemed unsuitable for warfarin at a large district general hospital
Use of the thrombin generation assay (calibrated automated thrombogram) in enoxaparin (low molecular weight heparin) treated pregnant patients
F8 and F9 mutations fail to co-segregate in a family with co-incident haemophilia A and B
Use of the thrombin generation assay (calibrated automated thrombogram) in patients with multiple myeloma and mantle cell lymphoma on thalidomide or lenalidamide therapy
Compliance with BCSH guidelines on inferior vena cava (IVC) filter insertion
Basal tissue factor levels are higher in patients with mantle cell lymphoma prior to lenalidamide therapy compared to controls
Treatment and complications of high international normalised ratios due to oral anticoagulation. An audit of practice of a large anticoagulation service
An audit of 80 patients between ages 85 and 90 attending the anticoagulant service at the University Hospital of South Manchester
Detecting sepsis beyond the activated partial thromboplastin time waveform
Clinical significance of differences between INR methods in over-anticoagulated patients
Lupus associated catastrophic antiphospholipid syndrome complicated by marantic endocarditis
Audit of vitamin K therapy for reversal of excessive anticoagulation
Newly diagnosed multiple myeloma (MM) patients requiring salvage therapy prior to high dose therapy (HDT) have equivalent progression free survival and overall survival to those receiving a single induction regimen
Bendamustine in relapsed or refractory indolent lymphoproliferative disorders - a single centre experience
Efficacy and safety of single-agent lenalidomide for relapsed/refractory mantle cell lymphoma (MCL): Preliminary results from a UK-based open-label phase II trial
Minimal residual disease monitoring in adult acute lymphoblastic leukaemia in the UK; a multi-centre laboratory feasibility study
Percutaneous vertebroplasty to treat painful myelomatous vertebral deposits - long term efficacy outcomes
An historical review of acute leukaemia in Papua New Guinea, 1958–2007, in preparation for the launch of the melanesian acute leukaemia biology project (MALBP) in 2010
Comparative outcomes of primary B and T cell non Hodgkin's lymphoma (NHL) of the gastrointestinal (GI) tract
Orbital relapse of mantle cell lymphoma and response to novel treatment regimens
Rituximab monotherapy in splenic marginal zone lymphoma instead of splenectomy
‘The Lost Tribe’: A retrospective audit of data quality and long-term follow-up arrangements among patients with haematological malignancies at St Bartholomew's Hospital, London (Bart's)
Myeloma: Discretionary laboratory requesting of serum protein electrophoresis is a major source of detection of clinically unsuspected new cases
Antithrombin replacement in adults undergoing induction therapy for acute lymphoblastic leukaemia
The use of locally-defined outcome data demonstrates that a threshold of 10% ZAP70 positive CLL-cells is effective at defining prognostically important subgroups of CLL in a single centre cohort
‘Rainy day’ stem cell harvests: A 5 year experience in two centres
Unexpected high incidence of cerebral sinus thrombosis in patients treated for acute lymphoblastic leukaemia: An unusual year or increasing incidence?
CEPP and R-CEPP chemotherapy in elderly patients with diffuse large B cell lymphoma
Severe 2009 H1N1 influenza in patients with haematological malignancies
A single-centre study of outcomes in patients over 70 years old treated for B-cell diffuse large cell lymphoma (DLBCL); the impact of co-morbidity scores
Epstein-Barr virus driven diffuse large B-cell lymphoma with co-existing follicular lymphoma
Atypical patterns of organ involvement by chronic lymphocytic leukaemia
Single centre experience of the management of post transplant lymphoproliferative disorder
Rituximab induced lung disease: A single centre experience and review of the literature
Does limiting antibiotic prophylaxis improve Clostridium difficile incidence rates in acute haematology patients?
Coverage of haemoglobinopathies in the undergraduate curriculum in the UK
Single dose ferric carboxymaltose compared with iron dextran for the treatment of iron deficiency anaemia
Anaemia and leukopenia in adults with lupus and anti-Ro/anti-La antibodies
The incidence of hypereosinophilia and its clinical significance at a district general hospital
Laboratory haematology validation and utility of the Cellavision DM96-automated digital microscopy haematological cell analysis system
Daptomycin use on a haematology unit in the UK
Pelvic fracture trauma leads to bone marrow dysfunction
National Haematology Undergraduate Teaching Survey: Defining the current state of play and prospects for a core curriculum
End-of-life and haematological malignancy: Destined to die in hospital?
Pilot assessment of malaria diagnosis and education using virtual microscopy for laboratories in Africa and developing nations
Superiority of the QBC over the Diamed OptiMAL-IT as a screening tool for malaria
Haematological characterization in N-Nitroso-N-ethylurea induced tumour bearing rats on oral administration of Pleurotus pulmonarius and P. ostreatus metabolites
Use of an electronic database to monitor complications of Hickman lines in a regional haematology unit
Microbiological surveillance in a regional haematology unit
An audit of the management of neutropenic sepsis at a regional haematology unit
A pilot prospective study of full blood examination parameters in pregnant women in the national capital district of Papua New Guinea
An audit of obstetric cases requiring specialist haematological input, referred during a period of 12 months to a single haematology unit in a medium sized district general hospital, highlighting the importance of specialist obstetric-haematology service in the district general hospital setting
Improved survival in haematological cancer in the Thames Valley Cancer Network
National Cancer Intelligence Network (NCIN) analyses of haematological malignancy. Incidence and survival by sex, ethnicity, deprivation, year of diagnosis and cancer network in the United Kingdom
Evaluation of the validity of UK NEQAS Hb A2 data for the NHS Sickle Cell and Thalassaemia Screening Programme
How well do foundation doctors know how to use oral anticoagulants?
Rapid response of myeloma hyperammonaemic encephalopathy to L-ornithine-L-aspartate therapy
Serum free light chain assay monitoring in plasma cell disorders - a single centre audit
Digital morphology: The UK NEQAS (H) scheme for continuing professional development
Pathology harmony: Consensus reference ranges for blood counts
Evalution of the impact of using the all methods trimmed mean on the performance assessment of haemoglobin estimation in UK NEQAS General Haematology surveys
Manual differential leucocyte counting: An assessment of performance in UK NEQAS General Haematology exercises
Developing an educational library of digital images from blood smears for UK NEQAS(H)
Practical difficulties with conducting non-interventional research for NICE technology appraisals: A case study in a quality of life assessment of chronic lymphocytic leukaemia patients
Five year retrospecitve analysis of septicaemic trends in haemato-oncology admissions to the Ulster Hospital Dundonald
Performance in parasite and blood film surveys by participants in the International External Quality Assessment Scheme for Haematology
Influenza A(H1N1) in patients with haematological malignancies. A review of our experience in South Devon Healthcare NHS Foundation Trust
Malarial episodes in paediatric oncology patients in Senegal: A retrospective, single-centre study
The management of port-a-cath infections in children with severe haemophilia
Near haploidy in ALL masquerading as high hyperdiploidy unmasked by DNA short tandem repeat polymorphism analysis
An evaluation of informed consent and patient understanding of blood transfusion
Abstract withdrawn.
The haemostatic impact of prion reduction in solvent detergent treated plasma
Severe haemolysis due to passenger lymphocyte syndrome after an ABO mismatched bowel transplant - a case report
Developing a new web based haemovigilance data capture system for SHOT
The cost of platelet transfusions: Managing thrombocytopenia of myelodysplastic syndromes in the United Kingdom
Management of haemorrhage associated with cardiac surgery in adults - a survey of protocols in UK centres
Where does blood go? Indications for red cell transfusion in the North of England from 1999 to 2009
Autologous peripheral progenitor cell harvesting in haematology patients: One centre experience
Anti-insulin receptor antibody mediated hypoglycaemia and insulin resistance following allogeneic stem-cell transplant
Efficacy and toxicity of cyclophosphamide 3 g/m2 and G-CSF for the mobilisation of PBSC in myeloma patients
High prevalence of dyslipidaemia in recipients of both allogeneic and autologous HSCT - a single centre experience
KIR genes are associated with incidence and duration of infection following autologous peripheral blood stem cell transplantation for multiple myeloma
Feasibility of safe ambulatory immediate post-autograft care in a district general hospital
Classic and overlap chronic graft- versus -host disease after T-replete reduced intensity conditioned sibling allograft usually starts within a year, causes prolonged morbidity but low mortality and is influenced by prophylactic methotrexate and ciclosporin dosing
The effects of IL-2 and IL-15 on NKT-cell activation and cytotoxicity against leukaemic cell lines
Weight loss is still a problem with reduced intensity conditioning transplants and modern supportive care
Being underweight may reduce your ability to mobilise stem cells
Fludarabine/cyclophosphamide non-myeloablative allogeneic stem cell transplantation for lymphoid malignancies
Retrospective study of clinical predictors of positive fungal cultures in recipients of allogeneic and autologous stem cell transplantation
Oncolytic reovirus as a treatment for AML
Is Bcr-Abl expression relevant for the survival of cancer stem cells in chronic myeloid leukaemia (CML)?
A novel RUNX1 mutation in an Irish kindred with familial platelet disorder with propensity to acute myeloid leukaemia
Development of a novel DNA vaccine encorporating a PASD1 analogue peptide which can enhance anti-leukaemia T cell responses in vitro and in vivo
Simultaneous analysis of specific T cell populations in acute leukaemia patients using the pMHC array
The clinical significance of protein phosphatase 2A (PP2A) in CML
Molecular responses to tyrosine kinase inhibitors in rare, variant ela2, e6a2 and e19a2 BCR-ABL chronic myeloid leukaemia
CCN3 enhances imatinib induced growth inhibition in chronic myeloid leukaemia
Identification of gene networks associated with acute myeloid leukaemia by comparative molecular methylation and expression profiling
Identification of microRNAs targeting CCN3 in chronic myeloid leukaemia
T-cell and B-cell responses after vaccination against influenza virus and pneumococcus in chronic phase CML patients treated with tyrosine kinase inhibitors
Uptake of synthetic low density lipoprotein by leukaemic stem cells - a potential targeted drug delivery strategy
Global methylation and expression changes in acute myeloid leukemia cell lines reveal clustering patterns after treatment with a demethylating agent
P-CrkL is not a surrogate of Bcr-Abl activity in vitro at short time-points
JAK2 is a relevant target in chronic myeloid leukaemia
5-aza-2′-deoxycytidine, a DNA methylation inhibitor, induces miRNA expression changes in acute myeloid leukaemia cell lines
Identification of a HOX-associated prognostic signature in AML
Coexistence of JAK2 positive myeloproliferative disorder and CML, a lesson from clinical practice
An audit of clinical practice in the diagnosis of myelodysplastic syndromes at UK haematology centres
Detection and referral of serum paraproteins identified by discretionary testing
Invasive pulmonary aspergillosis in hemato-oncology patients-early diagnosis by thoracic high resolution CT
English NHS in-patient bed days by cancer type (1997-2004): The impact of haematological malignancies
An analysis of AML treatment in a regional leukaemia unit: Nov 2006-Nov 2009
Adherence to imatinib therapy is the critical factor for achieving molecular responses in patients with chronic myeloid leukaemia
Imatinib plasma levels do not have prognostic value in determining molecular responses when adherence to therapy is taken in account in CML patients on long term imatinib treatment
Analysis of factors affecting outcome in recipients of bone marrow transplantation for myelodysplasia; a single centre's experience over a nine year period
Imatinib efficacy and tolerability in a ‘real world’ CML population study: Results from a West of Scotland and Lothian retrospective survey
Factors predicting outcome after unrelated donor stem cell transplantation in primary refractory acute myeloid leukaemia
An audit on the management of chronic myeloid leukaemia
Audit on the use of bortezomib {velcade} in cases of relapsed or refractory myeloma at Southampton General Hospital
Recurrence of pleural effusion on bosutinib therapy in a dasatinib treated patient with chronic myeloid leukaemia
A district general's experience on the toxicity associated with bortezomib therapy in myeloma
Efficacy and tolerability of dasatinib as a second line therapy for chronic myeloid leukaemia in the west of Scotland
Significant weight gain in patient with chronic myeloid leukaemia treated with imatinib therapy
Abstract withdrawn.
Ribavirin made easy. A collaborative approach to the development of guidance documents for the delivery of nebulised ribavirin using the Aiolos device
Improving the quality of peripheral neuropathy assessments for myeloma patients
‘Hospital 2 Home’. Getting it right for young people with cancer
“Getting the best of both worlds?” Uniting adult and paediatric practice in the treatment of febrile neutropenia
Improving the assessment of peripheral neuropathy in patients recieving thalidomide for multiple myeloma
Increased expression of YY1 protein predicts favourable outcome in follicular lymphoma
Mechanisms of oncolytic measles virus-induced neutrophil-mediated cytotoxicity
The polo like-kinase inhibitor BI2536 exhibits potent activity against plasma cells and represents a novel therapy in multiple myeloma
13q deletion size predicts disease progression and time to first treatment in patients with chronic lymphocytic leukaemia
A 9 series microRNA signature differentiates between germinal centre and activated B-cell-like diffuse large B-cell lymphoma cell lines
MicroRNA-155 and microRNA-29c are upregulated in chronic lymphocytic leukaemia
Investigating minimal residual disease in chronic lymphocytic leukaemia using fluorescent in situ hybridisation
Differential sensitivity of ATM mutant chronic lymphocytic leukaemia (CLL) cells to acetaminophen-induced cytotoxicity as a consequence of impaired redox stress responses
The serotonin receptor antagonist ondansetron up-regulates the production of nitric oxides in acute lymphoblastic leukaemia cells
Proteomics as a tool to determine the mechanisms of action of the B-cell receptor and identify novel prognostic biomarkers in chronic lymphocytic leukaemia
Mitoxantrone in combination with an inhibitor of DNA-dependent protein kinase: A potential therapy for poor risk B-cell chronic lymphocytic leukaemia
rs1045642 in P-glycoprotein; from genome to proteome in plasma cell myeloma
Evidence for a macromolecular complex in poor prognostic chronic lymphocytic leukaemia (CLL) that contains CD38, CD49d, CD44, MMP-9 And ZAP-70
Genome-wide analysis of chromosomal alterations in chronic lymphocytic leukaemia
The role of MDR1 (ABCB1) gene single nucleotide polymorphisms in chronic lymphocytic leukaemia
CD49d is an independent prognostic marker for time to first treatment and overall survival in chronic lymphocytic leukaemia (CLL)
Improving chelation therapy by monitoring T2* MRI cardiac scores and ferritin values in regularly transfused patients with thalassaemia
Management of acute chest syndrome in patients with sickle cell disease
Abstract withdrawn.
Abstract withdrawn.
What is missing?
Diagnostic and therapeutic challenges of an acute presentation of a rare unstable haemoglobin variant
An audit of the uptake of pneumococcus vaccination in adults with sickle cell disease
Spectrum of thalassaemia syndromes and structural hemoglobin variants encountered in a referral hospital in North India
An audit of the management of polycythaemia in a district general hospital
Trends in myocardial haemosiderosis relate to vitamin D status in transfusionally iron overloaded patients