Neurological concomitants of uveitis

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Aim:To describe the prevalence and types of neurological disease that occur in association with uveitis.Methods:Retrospective review of medical records of patients attending a tertiary referral uveitis service over a 15 year period.Results:Of 1450 patients with uveitis, 115 (7.9%) had neurological disease that was considered to be causally related to the eye inflammation. The most frequent neurological associations were Vogt-Koyanagi-Harada disease, primary central nervous system lymphoma, multiple sclerosis, and herpes virus infections.Conclusions:Neurological disease is common among patients attending a uveitis service. The distinctive characteristics of the uveal inflammation may be useful in diagnosing the neurological disease.

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