Introduction
A brief history of the British Pharmacological Society
The receptor concept: pharmacology's big idea
Agonist-activated ion channels
G-protein-coupled receptors: past, present and future
Pharmacology of intracellular signalling pathways
Heterotrimeric G-proteins: a short history
A short history of voltage-gated calcium channels
Potassium channels – multiplicity and challenges
Molecular targets underlying general anaesthesia
Neurotransmitter transporters and their impact on the development of psychopharmacology
Drug metabolism and pharmacogenetics: the British contribution to fields of international significance
The glutamate story
GABA and glycine as neurotransmitters: a brief history
Acetylcholine
Histamine and its receptors
Dopamine: the rewarding years
Neuropharmacology of 5-hydroxytryptamine
75 years of opioid research: the exciting but vain quest for the Holy Grail
Cannabinoid pharmacology: the first 66 years
Purinergic signalling
Prostaglandins, bioassay and inflammation
The discovery of nitric oxide and its role in vascular biology
Neuropeptides and their receptors: innovative science providing novel therapeutic targets
The attraction of chemokines as a target for specific anti-inflammatory therapy
Antiarrhythmic drug research
The role of inflammation in CNS injury and disease
Antiplatelet drugs
Phosphodiesterase inhibitors
Glucocorticoids: exemplars of multi-tasking
Tamoxifen (ICI46,474) as a targeted therapy to treat and prevent breast cancer
Neuromuscular block
Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness
Drugs for asthma
The future of pharmacology