Novel P2X7 receptor antagonists ease the pain
SK channels are on the move
Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states
Physiological and pathological changes in the redox state of human serum albumin critically influence its binding properties
Role of the nitric oxide pathway and the endocannabinoid system in neurogenic relaxation of corpus cavernosum from biliary cirrhotic rats
Endothelium-independent constriction of isolated, pressurized arterioles by N ω -nitro-L-arginine methyl ester (L-NAME)
Crocetin attenuates palmitate-induced insulin insensitivity and disordered tumor necrosis factor- α and adiponectin expression in rat adipocytes
Effect of two active compounds obtained from the essential oil of Cordia verbenacea on the acute inflammatory responses elicited by LPS in the rat paw
Role of neutrophil elastase in LTB4-induced neutrophil transmigration in vivo assessed with a specific inhibitor and neutrophil elastase deficient mice
Cryptotanshinone inhibits chemotactic migration in macrophages through negative regulation of the PI3K signaling pathway
The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter
Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels
The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors
Agonist-dependent consequences of proline to alanine substitution in the transmembrane helices of the calcitonin receptor
The synthetic cannabinoid HU210 induces spatial memory deficits and suppresses hippocampal firing rate in rats
Population pharmacokinetic modelling of non-linear brain distribution of morphine: influence of active saturable influx and P-glycoprotein mediated efflux
Influence of biophase distribution and P-glycoprotein interaction on pharmacokinetic-pharmacodynamic modelling of the effects of morphine on the EEG